MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

A growing number of functions are emerging for RNA interference (RNAi) in the nucleus, in
addition to well-characterized roles in post-transcriptional gene silencing in the cytoplasm …

Aggressive fungal pathogens such as Botrytis and Verticillium spp. cause severe crop
losses worldwide. We recently discovered that Botrytis cinerea delivers small RNAs (Bc …

Botrytis cinerea, the causative agent of gray mold disease, is an aggressive fungal pathogen
that infects more than 200 plant species. Here, we show that some B. cinerea small RNAs …

Genes in prokaryotic genomes are often arranged into clusters and co-transcribed into
polycistronic RNAs. Isolated examples of polycistronic RNAs were also reported in some …

RNAi is a potent technique for the knockdown of target genes. However, its potential off-
target effects limit the widespread applications in both reverse genetic analysis and genetic …

Since the establishment of a canonical animal microRNA biogenesis pathway driven by the
RNase III enzymes Drosha and Dicer, an unexpected variety of alternative mechanisms that …

The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici)
causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat …

Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

Vive la différence: biogenesis and evolution of microRNAs in plants and animals | Genome
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