Gut microbes as future therapeutics in treating inflammatory and infectious diseases: lessons from recent findings

S Mukherjee, N Joardar, S Sengupta… - The Journal of nutritional …, 2018 - Elsevier
The human gut microbiota has been the interest of extensive research in recent years and
our knowledge on using the potential capacity of these microbes are growing rapidly …

Complement and human T cell metabolism: Location, location, location

EE West, N Kunz, C Kemper - Immunological reviews, 2020 - Wiley Online Library
The complement system represents one of the evolutionary oldest arms of our immune
system and is commonly recognized as a liver‐derived and serum‐active system critical for …

[HTML][HTML] Toll-like receptor 2 in autoimmune inflammation

KE Marks, K Cho, C Stickling, JM Reynolds - Immune network, 2021 - ncbi.nlm.nih.gov
TLR signaling is critical for broad scale immune recognition of pathogens and/or danger
molecules. TLRs are particularly important for the activation and the maturation of cells …

Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration

KE Marks, S Flaherty, KM Patterson, M Stratton… - Cell reports, 2021 - cell.com
Pathogenic Th17 cells drive inflammation in autoimmune disease, yet the molecular
programming underlying Th17 cell pathogenicity remains insufficiently understood …

Microbially competent 3D Skin: a test system that reveals insight into host–microbe interactions and their potential toxicological impact

L Lemoine, R Dieckmann, S Al Dahouk, S Vincze… - Archives of …, 2020 - Springer
The skins microbiome is predominantly commensalic, harbouring a metabolic potential far
exceeding that of its host. While there is clear evidence that bacteria-dependent metabolism …

TLR activation and allergic disease: early life microbiome and treatment

KR Michels, NW Lukacs, W Fonseca - Current Allergy and Asthma …, 2018 - Springer
Abstract Purpose of Review Allergy and asthma are growing problems in the developed
world. The accelerated increase of these diseases may be related to microbiome …

Laboratory indicators for identifying hand, foot, and mouth disease severity: a systematic review and meta-analysis

Y Xie, Q Hu, W Jiang, W Ji, S Chen, Y Jin, G Duan - Vaccines, 2022 - mdpi.com
Objective: The purpose of this study is to study laboratory indicators for the identification of
hand, foot, and mouth disease (HFMD) severity. Methods: We searched PubMed, Embase …

Immunomodulation by the commensal microbiome during immune-targeted interventions: Focus on cancer immune checkpoint inhibitor therapy and vaccination

AL Reens, DJ Cabral, X Liang, JE Norton Jr… - Frontiers in …, 2021 - frontiersin.org
Emerging evidence in clinical and preclinical studies indicates that success of
immunotherapies can be impacted by the state of the microbiome. Understanding the role of …

TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection

SM Reba, Q Li, S Onwuzulike, N Nagy… - European Journal of …, 2024 - Wiley Online Library
Although a role for TLR2 on T cells has been indicated in prior studies, in vivo stimulation of
TLR2 on T cells by Mtb and its impact on Mtb infection has not been tested. Furthermore, it is …

Preliminary evaluation of selected inflammatory cytokine gene expression in lymphocytes isolated from whole human blood infected with trans‐anethole‐treated …

P Kwiatkowski, M Kurzawski… - Letters in Applied …, 2022 - academic.oup.com
In our previous study based on a whole‐blood model of sepsis infected with trans‐anethole
(TA)‐treated Staphylococcus aureus, we have found that innate immune response was more …