Progress in research on paclitaxel and tumor immunotherapy

L Zhu, L Chen - Cellular & molecular biology letters, 2019 - Springer
Paclitaxel is a well-known anticancer agent with a unique mechanism of action. It is
considered to be one of the most successful natural anticancer drugs available. This study …

Adverse effects of cancer chemotherapy: Anything new to improve tolerance and reduce sequelae?

K Nurgali, RT Jagoe, R Abalo - Frontiers in pharmacology, 2018 - frontiersin.org
The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

Exosomal LOC85009 inhibits docetaxel resistance in lung adenocarcinoma through regulating ATG5-induced autophagy

Z Yu, H Tang, S Chen, Y Xie, L Shi, S Xia… - Drug Resistance …, 2023 - Elsevier
Aims This study aims at investigating the role of a neighbor long non-coding RNA (lncRNA)
of HDAC4 (LOC85009) in docetaxel (DTX) resistance of lung adenocarcinoma (LUAD) …

Long-term effects, pathophysiological mechanisms, and risk factors of chemotherapy-induced peripheral neuropathies: a comprehensive literature review

N Kerckhove, A Collin, S Condé, C Chaleteix… - Frontiers in …, 2017 - frontiersin.org
Neurotoxic anticancer drugs, such as platinum-based anticancer drugs, taxanes, vinca
alkaloids, and proteasome/angiogenesis inhibitors are responsible for chemotherapy …

Drug metabolites and their effects on the development of adverse reactions: Revisiting Lipinski's Rule of Five

CM Chagas, S Moss, L Alisaraie - International journal of pharmaceutics, 2018 - Elsevier
Many studies have shown that toxicities of anticancer drugs and their adverse effects are
related to their chemical structure and high molecular weight that may result in a number of …

Comparison of anticancer drug toxicities: paradigm shift in adverse effect profile

D Basak, S Arrighi, Y Darwiche, S Deb - Life, 2021 - mdpi.com
The inception of cancer treatment with chemotherapeutics began in the 1940s with nitrogen
mustards that were initially employed as weapons in World War II. Since then, treatment …

[HTML][HTML] Chemotherapeutic agents for the treatment of metastatic breast cancer: An update

M Abotaleb, P Kubatka, M Caprnda, E Varghese… - Biomedicine & …, 2018 - Elsevier
Breast cancer is the second greatest cause of death among women worldwide; it comprises
a group of heterogeneous diseases that evolves due to uncontrolled cellular growth and …

Effects of progressive muscle relaxation and mindfulness meditation on fatigue, coping styles, and quality of life in early breast cancer patients: An assessor blinded …

ZG Metin, C Karadas, N Izgu, L Ozdemir… - European Journal of …, 2019 - Elsevier
Purpose This study aimed to investigate the effects of progressive muscle relaxation (PMR)
and mindfulness meditation (MM) on fatigue, coping styles, and quality of life (QOL) in …

Docetaxel: An update on its molecular mechanisms, therapeutic trajectory and nanotechnology in the treatment of breast, lung and prostate cancer

M Imran, S Saleem, A Chaudhuri, J Ali… - Journal of Drug Delivery …, 2020 - Elsevier
Amongst the various microtubule-targeting agents, Docetaxel (DTX) has gained immense
attention in cancer chemotherapy due to its good therapeutic index. DTX belongs to the …

Injectable dual thermoreversible hydrogel for sustained intramuscular drug delivery

FU Din, JS Kim, HC Lee, S Cheon, MR Woo… - Journal of Controlled …, 2024 - Elsevier
Herein, we reported novel docetaxel-decorated solid lipid nanoparticle (DCT-SLN)-loaded
dual thermoreversible system (DCT-DRTS) for intramuscular administration with reduced …