With the gradual demographic shift toward an aging and obese society, an increasing
number of patients are suffering from bone and cartilage injuries. However, conventional …

Osteochondral defect management and repair remain a significant challenge in orthopedic
surgery. Osteochondral defects contain damage to both the articular cartilage as well as the …

The management and reconstruction of damaged or diseased skeletal tissues have
remained a significant global healthcare challenge. The limited efficacy of conventional …

The treatment of articular cartilage defects seems to be one of the greatest challenges in
modern orthopaedics. From a medical point of view there are 3 main goals to achieve for …

Today, articular cartilage damage is a major health problem, affecting people of all ages.
The existing conventional articular cartilage repair techniques, such as autologous …

Completely repairing of damaged cartilage is a difficult procedure. In recent years, the use of
tissue engineering approach in which scaffolds play a vital role to regenerate cartilage has …

Herein we review the state-of-the-art in tissue engineering for repair of articular cartilage.
First, we describe the molecular, cellular, and histologic structure and function of …

Rationale: Articular cartilage injury is quite common. However, post-injury cartilage repair is
challenging and often requires medical intervention, which can be aided by 3D printed …

Nanotechnology has changed science in the last three decades. Recent applications of
nanotechnology in the disciplines of medicine and biology have enhanced medical …

Direct injection of chondrocytes in a minimally invasive way has been regarded as the
significantly potential treatment for cartilage repair due to their ability to fill various irregular …