The role of microRNAs in epigenetic regulation of signaling pathways in neurological pathologies

PP Tregub, I Ibrahimli, AS Averchuk… - International journal of …, 2023 - mdpi.com
In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

Novel approaches to the establishment of local microenvironment from resorbable biomaterials in the brain in vitro models

NA Kolotyeva, FN Gilmiyarova, AS Averchuk… - International Journal of …, 2023 - mdpi.com
The development of brain in vitro models requires the application of novel biocompatible
materials and biopolymers as scaffolds for controllable and effective cell growth and …

Investigation of high-dose radiotherapy's effect on brain structure aggravated cognitive impairment and deteriorated patient psychological status in brain tumor …

J Ma, H Cao, D Hou, W Wang, T Liu - Scientific Reports, 2024 - nature.com
This study aims to investigate the potential impact of high-dose radiotherapy (RT) on brain
structure, cognitive impairment, and the psychological status of patients undergoing brain …

Blood vessels as a key mediator for ethanol toxicity: implication for neuronal damage

K Nakayama, H Hasegawa - Life, 2022 - mdpi.com
Excessive intake of ethanol is associated with severe brain dysfunction, and the subsequent
neurological and behavioral abnormalities are well-established social risks. Many research …

[HTML][HTML] Thymosin beta 10 loaded ZIF-8/sericin hydrogel promoting angiogenesis and osteogenesis for bone regeneration

J Gao, J Ren, H Ye, W Chu, X Ding, L Ding… - International Journal of …, 2024 - Elsevier
Angiogenesis is pivotal for osteogenesis during bone regeneration. A hydrogel that
promotes both angiogenesis and osteogenesis is essential in bone tissue engineering …

Cerebrovascular Remodeling and the Role of Vascular Endothelial Growth Factor in the Epileptic Brain and Pharmacoresistance

JL Castañeda-Cabral, ME Ureña-Guerrero… - … in Epilepsy: From …, 2023 - Springer
The neurovascular unit plays a relevant role in normal situations and pathological conditions
involving the nervous system. In epileptic conditions, cerebrovascular remodeling is a …

[PDF][PDF] 基于改良大鼠双侧颈总动脉结扎法建立血管性痴呆模型探讨脑血流量变化规律及对血管新生相关蛋白的影响

陈婕, 唐鑫, 陈盼, 谢紫薇, 谢海花, 张泓… - 中国实验动物 …, 2023 - zgbjyx.cnjournals.com
目的通过改良大鼠双侧颈总动脉结扎法建立血管性痴呆(cascular dementia, VD)
大鼠模型观察其脑血流量变化规律及血管新生蛋白表达等变化. 方法将36 只SD …

[HTML][HTML] 流体剪切力调控血脑屏障的力学生物学机制研究

聆语杜, 博闻许, 琳程, 红燕岳, 怀奕张… - Journal of Sichuan …, 2024 - ncbi.nlm.nih.gov
目的血脑屏障( blood-brain barrier, BBB) 主要由脑微血管内皮细胞组成。
本研究以大鼠脑微血管内皮细胞( rat brain microvascular endothelial cells, rBMECs) …

流体剪切力调控血脑屏障的力学生物学机制研究

杜聆语, 许博闻, 程琳, 岳红燕, 张怀奕, 沈阳 - europepmc.org
目的血脑屏障(blood-brain barrier, BBB) 主要由脑微血管内皮细胞组成. 本研究以大鼠脑微血管
内皮细胞(rat brain microvascular endothelial cells, rBMECs) 为模式细胞, 探索正常生理 …

Mechanobiological Mechanisms Involved in the Regualation of the Blood-Brain Barrier by Fluid Shear Force

DU Lingyu, XU Bowen, C Lin… - JOURNAL OF …, 2024 - ykxb.scu.edu.cn
Objective To explore the mechanobiological mechanism of fluid shear force (FSF) on the
protection, injury, and destruction of the structure and function of the blood-brain barrier …