Coronary restenosis is a reparative response to arterial injury during angioplasty, and
remains a major clinical problem. The reasons for treatment failures likely stem from our …

Cardiovascular disease is the number one cause of death among women, accounting for
nearly 50% of female deaths. Statistics show that women on average develop …

The fibroblast or heparin-binding growth factors (HBGFs) are thought to be modulators of
cell growth and migration, angiogenesis, wound repair, neurite extension, and mesoderm …

The proliferative potential of human diploid endothelial cells is finite, and cellular
senescence in vitro is accompanied by the failure of the endothelial cell to respond to …

Heparin-binding growth factor-1 (HBGF-1) is an angiogenic polypeptide mitogen for
mesoderm-and neuroectoderm-derived cells in vitro and remains biologically active after …

The retinal pigmented epithelium (RPE) plays a major role in normal and exaggerated
retinal wound repair; the latter can result in epiretinal membrane formation and loss of …

Cytokines play a key role in mutual influence of the immunological, endocrine and CNS
systems. It has been proven that proinflammatory ILs may intensify the cascade of …

Background The purpose of this pilot study was to identify biological risk factors for
restenosis after percutaneous transluminal coronary angioplasty (PTCA) to predict the long …

Migration of medial smooth muscle cells (SMC) into the intima is important in intimal
thickening of atherosclerotic tissues. To study the functions of three isoforms of platelet …

Proliferation of vascular cells has been previously shown to contribute to spontaneous
development of coronary collaterals. Recent studies from several laboratories have …