Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

mRNA vaccines for infectious diseases: principles, delivery and clinical translation

N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …

[HTML][HTML] Respiratory syncytial virus prefusion F protein vaccine in older adults

A Papi, MG Ison, JM Langley, DG Lee… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is an important cause of acute respiratory
infection, lower respiratory tract disease, clinical complications, and death in older adults …

Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults

EE Walsh, G Pérez Marc, AM Zareba… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) infection causes considerable illness in older
adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein–based …

Prefusion F protein–based respiratory syncytial virus immunization in pregnancy

EAF Simões, KJ Center, ATN Tita… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV), a major cause of illness and death in infants
worldwide, could be prevented by vaccination during pregnancy. The efficacy …

Single-dose nirsevimab for prevention of RSV in preterm infants

MP Griffin, Y Yuan, T Takas… - … England Journal of …, 2020 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is the most common cause of lower
respiratory tract infection in infants, and a need exists for prevention of RSV in healthy …

Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Respiratory syncytial virus–associated hospitalizations among young children: 2015–2016

B Rha, AT Curns, JY Lively, AP Campbell… - …, 2020 - publications.aap.org
BACKGROUND: Respiratory syncytial virus (RSV) is a major cause of hospitalized acute
respiratory illness (ARI) among young children. With RSV vaccines and immunoprophylaxis …

BCG-induced cross-protection and development of trained immunity: implication for vaccine design

C Covián, A Fernández-Fierro, A Retamal-Díaz… - Frontiers in …, 2019 - frontiersin.org
The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the
ability to induce non-specific cross-protection against pathogens that might be unrelated to …

Potentialities of selenium nanoparticles in biomedical science

V Nayak, KRB Singh, AK Singh, RP Singh - New Journal of Chemistry, 2021 - pubs.rsc.org
Nanotechnology is defined as the branch of science dealing with extremely small-sized
particles with a size in the range of 1–100 nm, which are termed nanoparticles. Due to the …