Prostate cancer review: genetics, diagnosis, treatment options, and alternative approaches
M Sekhoacha, K Riet, P Motloung, L Gumenku… - Molecules, 2022 - mdpi.com
Simple Summary Prostate cancer affects men of all racial and ethnic groups and leads to
higher rates of mortality in those belonging to a lower socioeconomic status due to late …
higher rates of mortality in those belonging to a lower socioeconomic status due to late …
The 2016 WHO classification of tumours of the urinary system and male genital organs—part B: prostate and bladder tumours
PA Humphrey, H Moch, AL Cubilla, TM Ulbright… - European urology, 2016 - Elsevier
It has been 12 yr since the publication of the last World Health Organization (WHO)
classification of tumours of the prostate and bladder. During this time, significant new …
classification of tumours of the prostate and bladder. During this time, significant new …
Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
H Song, HNW Weinstein, P Allegakoen… - Nature …, 2022 - nature.com
Prostate cancer is the second most common malignancy in men worldwide and consists of a
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …
mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor …
Recent advances in prostate cancer treatment and drug discovery
E Nevedomskaya, SJ Baumgart… - International journal of …, 2018 - mdpi.com
Novel drugs, drug sequences and combinations have improved the outcome of prostate
cancer in recent years. The latest approvals include abiraterone acetate, enzalutamide and …
cancer in recent years. The latest approvals include abiraterone acetate, enzalutamide and …
Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer
Tumour heterogeneity in primary prostate cancer is a well-established phenomenon.
However, how the subclonal diversity of tumours changes during metastasis and …
However, how the subclonal diversity of tumours changes during metastasis and …
Mining cancer methylomes: prospects and challenges
There are over 28 million CpG sites in the human genome. Assessing the methylation status
of each of these sites will be required to understand fully the role of DNA methylation in …
of each of these sites will be required to understand fully the role of DNA methylation in …
Genomic predictors of outcome in prostate cancer
Context Given the highly variable behavior and clinical course of prostate cancer (PCa) and
the multiple available treatment options, a personalized approach to oncologic risk …
the multiple available treatment options, a personalized approach to oncologic risk …
Evolution of androgen receptor targeted therapy for advanced prostate cancer
The discovery of androgen dependence in prostate cancer in 1941 by Huggins and
colleagues has remained the backbone for the treatment of this disease. However, although …
colleagues has remained the backbone for the treatment of this disease. However, although …
A patient‐derived explant (PDE) model of hormone‐dependent cancer
MM Centenera, TE Hickey, S Jindal… - Molecular …, 2018 - Wiley Online Library
Breast and prostate cancer research to date has largely been predicated on the use of cell
lines in vitro or in vivo. These limitations have led to the development of more clinically …
lines in vitro or in vivo. These limitations have led to the development of more clinically …
Circulating microRNA signature for the diagnosis of very high-risk prostate cancer
AH Alhasan, AW Scott, JJ Wu, G Feng… - Proceedings of the …, 2016 - National Acad Sciences
We report the identification of a molecular signature using the Scano-miR profiling platform
based on the differential expression of circulating microRNAs (miRNA, miR) in serum …
based on the differential expression of circulating microRNAs (miRNA, miR) in serum …