[HTML][HTML] The mare: a pertinent model for human assisted reproductive technologies?

A Benammar, E Derisoud, F Vialard, E Palmer… - Animals, 2021 - mdpi.com
Simple Summary Artificial reproduction techniques (ART) are used widely in human
medicine to overcome infertility, with about one in seven couples being concerned in the …

Endoplasmic reticulum stress: a key regulator of the follicular microenvironment in the ovary

M Harada, N Takahashi, JM Azhary… - Molecular human …, 2021 - academic.oup.com
Intra-ovarian local factors regulate the follicular microenvironment in coordination with
gonadotrophins, thus playing a crucial role in ovarian physiology as well as pathological …

[HTML][HTML] Oocyte metabolic function, lipid composition, and developmental potential are altered by diet in older mares

GD Catandi, L LiPuma, YM Obeidat… - …, 2022 - rep.bioscientifica.com
Dietary supplementation is the most feasible method to improve oocyte function and
developmental potential in vivo. During three experiments, oocytes were collected from …

Obesity leads to distinct metabolomic signatures in follicular fluid of women undergoing in vitro fertilization

ML Ruebel, BD Piccolo, KE Mercer… - American Journal …, 2019 - journals.physiology.org
Although obesity negatively influences the metabolic homeostasis of cells within a broad
range of tissues, its impact on oocyte metabolism is not fully understood. Prior evidence …

Dual role for the unfolded protein response in the ovary: adaption and apoptosis

N Huang, Y Yu, J Qiao - Protein & cell, 2017 - academic.oup.com
The endoplasmic reticulum (ER) is the principal organelle responsible for several specific
cellular functions including synthesis and folding of secretory or membrane proteins, lipid …

Obesity in mares promotes uterine inflammation and alters embryo lipid fingerprints and homeostasis

DR Sessions-Bresnahan, AL Heuberger… - Biology of …, 2018 - academic.oup.com
Maternal body composition can be an important determinant for development of obesity and
metabolic syndrome in adult offspring. Obesity-related outcomes in offspring may include …

[HTML][HTML] Metabolomic alternations of follicular fluid of obese women undergoing in-vitro fertilization treatment

J Song, S Xiang, C Pang, J Guo, Z Sun - Scientific Reports, 2020 - nature.com
Obesity exerts negative effects on the metabolic homeostasis of cells in various tissues, but
how it influences ovum metabolism is not fully understood. Previous studies demonstrate …

Effect of body weight on metabolic hormones and fatty acid metabolism in follicular fluid of women undergoing in vitro fertilization: a pilot study

L Bou Nemer, H Shi, BR Carr, RA Word… - Reproductive …, 2019 - journals.sagepub.com
Introduction: Obesity is an epidemic affecting more than one-third of adults in the United
States. Obese women experience decreased fertility, explained in part by oocyte quality …

[HTML][HTML] Analysis of the equine “cumulome” reveals major metabolic aberrations after maturation in vitro

J Walter, F Huwiler, C Fortes, J Grossmann… - Bmc Genomics, 2019 - Springer
Background Maturation of oocytes under in vitro conditions (IVM) results in impaired
developmental competence compared to oocytes matured in vivo. As oocytes are closely …

[HTML][HTML] The effects of obesity and insulin dysregulation on mare reproduction, pregnancy, and foal health: a review

I Hallman, N Karikoski, M Kareskoski - Frontiers in Veterinary Science, 2023 - frontiersin.org
Obesity is a growing welfare concern in modern equine populations and predisposes horses
to disturbances in energy metabolism such as insulin dysregulation. However, equine …