The pig as a preclinical traumatic brain injury model: current models, functional outcome measures, and translational detection strategies

HA Kinder, EW Baker, FD West - Neural regeneration research, 2019 - journals.lww.com
Traumatic brain injury (TBI) is a major contributor of long-term disability and a leading cause
of death worldwide. A series of secondary injury cascades can contribute to cell death …

Diffuse axonal injury: clinical prognostic factors, molecular experimental models and the impact of the trauma related oxidative stress. An extensive review concerning …

M Palmieri, A Frati, A Santoro, P Frati… - International Journal of …, 2021 - mdpi.com
Traumatic brain injury (TBI) is a condition burdened by an extremely high rate of morbidity
and mortality and can result in an overall disability rate as high as 50% in affected …

[HTML][HTML] Development and characterization of transfontanelle photoacoustic imaging system for detection of intracranial hemorrhages and measurement of brain …

R Manwar, K Kratkiewicz, S Mahmoodkalayeh, A Hariri… - Photoacoustics, 2023 - Elsevier
We have developed and optimized an imaging system to study and improve the detection of
brain hemorrhage and to quantify oxygenation. Since this system is intended to be used for …

Application of machine learning to predict the outcome of pediatric traumatic brain injury

T Thara, O Thakul - Chinese Journal of Traumatology, 2021 - mednexus.org
Purpose: Traumatic brain injury (TBI) generally causes mortality and disability, particularly in
children. Machine learning (ML) is a computer algorithm, applied as a clinical prediction tool …

Polarization of microglia to the M2 phenotype in a peroxisome proliferator-activated receptor gamma–dependent manner attenuates axonal injury induced by …

L Wen, W You, H Wang, Y Meng, J Feng… - Journal of …, 2018 - liebertpub.com
Increasing evidence indicates that activated microglia play an important role in the
inflammatory response following traumatic brain injury (TBI). Inhibiting M1 and stimulating …

Plasma neurofilament light admission levels and development of axonal pathology in mild traumatic brain injury

I Hossain, M Mohammadian, HR Maanpää… - BMC neurology, 2023 - Springer
Background It is known that blood levels of neurofilament light (NF-L) and diffusion-weighted
magnetic resonance imaging (DW-MRI) are both associated with outcome of patients with …

Impact of traumatic brain injury on sleep: an overview

R Aoun, H Rawal, H Attarian… - Nature and science of …, 2019 - Taylor & Francis
Traumatic brain injury (TBI) is a global health problem that affects millions of civilians,
athletes, and military personnel yearly. Sleeping disorders are one of the underrecognized …

Using trauma registry data to predict prolonged mechanical ventilation in patients with traumatic brain injury: Machine learning approach

A Abujaber, A Fadlalla, D Gammoh, H Abdelrahman… - PLoS one, 2020 - journals.plos.org
Objectives We aimed to build a machine learning predictive model to predict the risk of
prolonged mechanical ventilation (PMV) for patients with Traumatic Brain Injury (TBI) …

[HTML][HTML] Diffuse axonal injury

FB Mesfin, N Gupta, RS Taylor - 2017 - europepmc.org
Diffuse Axonal Injury - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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Pediatric head trauma: a review and update

RN Gelineau-Morel, TP Zinkus… - Pediatrics in …, 2019 - publications.aap.org
There is still a considerable amount of confusion when it comes to managing concussions.
An excessive number of head computed tomographic scans are being obtained for …