[HTML][HTML] Functional and pathologic association of aminoacyl-tRNA synthetases with cancer
Although key tumorigenic and tumor-suppressive factors have been unveiled over the last
several decades, cancer remains the most life-threatening disease. Multiomic analyses of …
several decades, cancer remains the most life-threatening disease. Multiomic analyses of …
[HTML][HTML] The nuts and bolts of PIN auxin efflux carriers
M Zwiewka, V Bilanovičová, YW Seifu… - Frontiers in Plant …, 2019 - frontiersin.org
The plant-specific proteins named PIN-FORMED (PIN) efflux carriers facilitate the direction
of auxin flow and thus play a vital role in the establishment of local auxin maxima within …
of auxin flow and thus play a vital role in the establishment of local auxin maxima within …
[HTML][HTML] Selective neuronal vulnerability in Alzheimer's disease: a network-based analysis
A major obstacle to treating Alzheimer's disease (AD) is our lack of understanding of the
molecular mechanisms underlying selective neuronal vulnerability, a key characteristic of …
molecular mechanisms underlying selective neuronal vulnerability, a key characteristic of …
The Plant PTM Viewer, a central resource for exploring plant protein modifications
P Willems, A Horne, T Van Parys… - The Plant …, 2019 - Wiley Online Library
Post‐translational modifications (PTM s) of proteins are central in any kind of cellular
signaling. Modern mass spectrometry technologies enable comprehensive identification and …
signaling. Modern mass spectrometry technologies enable comprehensive identification and …
[HTML][HTML] FOXO family isoforms
BF Santos, I Grenho, PJ Martel, BI Ferreira… - Cell Death & …, 2023 - nature.com
FOXO family of proteins are transcription factors involved in many physiological and
pathological processes including cellular homeostasis, stem cell maintenance, cancer …
pathological processes including cellular homeostasis, stem cell maintenance, cancer …
qPTM: an updated database for PTM dynamics in human, mouse, rat and yeast
K Yu, Y Wang, Y Zheng, Z Liu, Q Zhang… - Nucleic Acids …, 2023 - academic.oup.com
Post-translational modifications (PTMs) are critical molecular mechanisms that regulate
protein functions temporally and spatially in various organisms. Since most PTMs are …
protein functions temporally and spatially in various organisms. Since most PTMs are …
CPLM 4.0: an updated database with rich annotations for protein lysine modifications
W Zhang, X Tan, S Lin, Y Gou, C Han… - Nucleic Acids …, 2022 - academic.oup.com
Here, we reported the compendium of protein lysine modifications (CPLM 4.0, http://cplm.
biocuckoo. cn/), a data resource for various post-translational modifications (PTMs) …
biocuckoo. cn/), a data resource for various post-translational modifications (PTMs) …
Alterations in the global proteome and phosphoproteome in third generation EGFR TKI resistance reveal drug targets to circumvent resistance
X Zhang, TK Maity, KE Ross, Y Qi, CM Cultraro… - Cancer research, 2021 - AACR
Lung cancer is the leading cause of cancer mortality worldwide. The treatment of patients
with lung cancer harboring mutant EGFR with orally administered EGFR tyrosine kinase …
with lung cancer harboring mutant EGFR with orally administered EGFR tyrosine kinase …
[HTML][HTML] Nucleolin: a cell portal for viruses, bacteria, and toxins
The main localization of nucleolin is the nucleolus, but this protein is present in multiple
subcellular sites, and it is unconventionally secreted. On the cell surface, nucleolin acts as a …
subcellular sites, and it is unconventionally secreted. On the cell surface, nucleolin acts as a …
EPSD: a well-annotated data resource of protein phosphorylation sites in eukaryotes
As an important post-translational modification (PTM), protein phosphorylation is involved in
the regulation of almost all of biological processes in eukaryotes. Due to the rapid progress …
the regulation of almost all of biological processes in eukaryotes. Due to the rapid progress …