The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …

Migraine is a highly prevalent and disabling neurological disorder associated with a wide
range of psychiatric comorbidities. In this manuscript, we provide an overview of the link …

Controlled breathwork practices have emerged as potential tools for stress management
and well-being. Here, we report a remote, randomized, controlled study (NCT05304000) of …

It is widely thought that phasic and sustained responses to threat reflect dissociable circuits
centered on the central nucleus of the amygdala (Ce) and the bed nucleus of the stria …

Anxiety disorders impose a staggering burden on public health, underscoring the need to
develop a deeper understanding of the distributed neural circuits underlying extreme fear …

A growing body of researches support a role for dysfunction of serotoninergic,
noradrenergic, and dopaminergic systems in the neurobiological processes involved in …

Substance use disorders (SUDs) are a growing public health concern with only a limited
number of approved treatments. However, even approved treatments are subject to limited …

Dispositional negativity—the propensity to experience and express more frequent, intense,
or enduring negative affect—is a fundamental dimension of childhood temperament and …

The bed nucleus of the stria terminalis (BNST) has been implicated in conditioned fear and
anxiety, but the specific factors that engage the BNST in defensive behaviors are unclear …

It is unknown whether indoles, metabolites of tryptophan that are derived entirely from
bacterial metabolism in the gut, are associated with symptoms of depression and anxiety …