Stimuli‐responsive biomaterials: Scaffolds for stem cell control

A Gelmi, CE Schutt - Advanced Healthcare Materials, 2021 - Wiley Online Library
Stem cell fate is closely intertwined with microenvironmental and endogenous cues within
the body. Recapitulating this dynamic environment ex vivo can be achieved through …

[HTML][HTML] Fracture non-union: a review of clinical challenges and future research needs

SK Stewart - Malaysian orthopaedic journal, 2019 - ncbi.nlm.nih.gov
Non-union of bone following fracture is an orthopaedic condition with a high morbidity and
clinical burden. Despite its estimated global prevalence of nine million annually, the limit of …

Mechanotransduction in osteogenesis

S Stewart, A Darwood, S Masouros… - Bone & joint …, 2020 - boneandjoint.org.uk
Bone is one of the most highly adaptive tissues in the body, possessing the capability to alter
its morphology and function in response to stimuli in its surrounding environment. The ability …

[HTML][HTML] Modification of the surface nanotopography of implant devices: A translational perspective

K Harawaza, B Cousins, P Roach, A Fernandez - Materials Today Bio, 2021 - Elsevier
There is an increasing need for the development of superior, safe, and more sophisticated
implants, especially as our society historically has been moving towards an increasingly …

[HTML][HTML] Bioscaffolds embedded with regulatory modules for cell growth and tissue formation: A review

P Wang, Y Sun, X Shi, H Shen, H Ning, H Liu - Bioactive Materials, 2021 - Elsevier
The demand for artificial organs has greatly increased because of various aging-associated
diseases and the wide need for organ transplants. A recent trend in tissue engineering is the …

Mechanotransducive surfaces for enhanced cell osteogenesis, a review

RC Delint, H Jaffery, MI Ishak, AH Nobbs, B Su… - Biomaterials …, 2024 - Elsevier
Novel strategies employing mechano-transducing materials eliciting biological outcomes
have recently emerged for controlling cellular behaviour. Targeted cellular responses are …

[HTML][HTML] Magneto-mechanically induced antimicrobial properties of cone-like shaped surfaces

J Marqués-Marchán, MM Fernandes… - Applied Materials …, 2023 - Elsevier
Hygienic surfaces that prevent the proliferation of harmful microorganisms are required in a
large variety of environments, including medical areas. Novel strategies are being …

Advances in natural and synthetic macromolecules with stem cells and extracellular vesicles for orthopedic disease treatment

S Wang, Z Jia, M Dai, X Feng, C Tang, L Liu… - International Journal of …, 2024 - Elsevier
Serious orthopedic disorders resulting from myriad diseases and impairments continue to
pose a considerable challenge to contemporary clinical care. Owing to its limited …

Vibropolyfection: coupling polymer-mediated gene delivery to mechanical stimulation to enhance transfection of adherent cells

F Ponti, N Bono, L Russo, P Bigini, D Mantovani… - Journal of …, 2022 - Springer
Background With the success of recent non-viral gene delivery-based COVID-19 vaccines,
nanovectors have gained some public acceptance and come to the forefront of advanced …

Gene expression during THP-1 differentiation is influenced by vitamin D3 and not vibrational mechanostimulation

T Simakou, R Freeburn, FL Henriquez - PeerJ, 2021 - peerj.com
Background In injury or infection, monocytes migrate into the affected tissues from circulation
and differentiate into macrophages which are subsequently involved in the inflammatory …