The role of polyphenols in overcoming cancer drug resistance: A comprehensive review

P Maleki Dana, F Sadoughi, Z Asemi… - Cellular & molecular …, 2022 - Springer
Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery.
However, cancers often develop resistance against drugs, leading to failure of treatment and …

Pomegranate peel and peel extracts: Chemistry and food features

S Akhtar, T Ismail, D Fraternale, P Sestili - Food chemistry, 2015 - Elsevier
The present review focuses on the nutritional, functional and anti-infective properties of
pomegranate (Punica granatum L.) peel (PoP) and peel extract (PoPx) and on their …

Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

JM Lü, PH Lin, Q Yao, C Chen - Journal of cellular and …, 2010 - Wiley Online Library
Introduction• Free radical scavenging‐Scavenging superoxide and other ROS‐Scavenging
hydroxyl radical and other ROS‐Stable radical scavenging• Metal ion (Fe2+, Fe3+, Cu2+ …

A review of the antioxidant mechanisms of polyphenol compounds related to iron binding

NR Perron, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
In this review, primary attention is given to the antioxidant (and prooxidant) activity of
polyphenols arising from their interactions with iron both in vitro and in vivo. In addition, an …

Coordination-driven multistep assembly of metal–polyphenol films and capsules

MA Rahim, H Ejima, KL Cho, K Kempe… - Chemistry of …, 2014 - ACS Publications
We report the assembly of metal-polyphenol complex (MPC) films and capsules through the
sequential deposition of iron (III) ions (Fe (III)) and a natural polyphenol, tannic acid (TA) …

[PDF][PDF] Los flavonoides: propiedades y acciones antioxidantes

S Martínez-Flórez, J González-Gallego… - Nutrición …, 2002 - academia.edu
Los flavonoides son compuestos fenólicos constituyentes de la parte no energética de la
dieta humana. Se encuentran en vegetales, semillas, frutas y en bebidas como vino y …

Plant food residues as a source of nutraceuticals and functional foods

T Varzakas, G Zakynthinos, F Verpoort - Foods, 2016 - mdpi.com
This chapter describes the use of different plant and vegetable food residues as
nutraceuticals and functional foods. Different nutraceuticals are mentioned and explained …

Cardiovascular effects of flavonoids are not caused only by direct antioxidant activity

P Mladěnka, L Zatloukalová, T Filipský… - Free Radical Biology and …, 2010 - Elsevier
Epidemiological, as well as most in vivo, studies suggest that flavonoids have a positive
influence on various cardiovascular diseases. Traditionally, these effects were only …

Response of the antioxidant defense system to tert‐butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2)

M Alía, S Ramos, R Mateos, L Bravo… - Journal of biochemical …, 2005 - Wiley Online Library
The aim of this work was to investigate the response of the antioxidant defense system to
two oxidative stressors, hydrogen peroxide and tert‐butyl hydroperoxide, in HepG2 cells in …

Phenolic compounds protect HepG2 cells from oxidative damage: relevance of glutathione levels

CF Lima, M Fernandes-Ferreira, C Pereira-Wilson - Life sciences, 2006 - Elsevier
In the present work, the potential hepatoprotective effects of five phenolic compounds
against oxidative damages induced by tert-butyl hydroperoxide (t-BHP) were evaluated in …