Like normal hematopoietic stem cells, leukemic stem cells depend on their bone marrow
(BM) microenvironment for survival, but the underlying mechanisms remain largely …

Myeloproliferative neoplasms (MPNs) are diseases caused by mutations in the
haematopoietic stem cell (HSC) compartment. Most MPN patients have a common acquired …

Mesenchymal stem cells (MSCs) and osteolineage cells contribute to the hematopoietic
stem cell (HSC) niche in the bone marrow of long bones. However, their developmental …

Abstract Aims Epidermal Neural Crest Stem Cells (EPI-NCSCs) have emerged as
prospective ideal candidates to meet the fundamental requirements of cell-based therapies …

Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that
recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor …

Neuroblastoma is an embryonal tumor with a heterogeneous clinical course. The tumor is
presumed to be derived from the neural crest, but the cells of origin remain to be determined …

Macroautophagy/autophagy is emerging as an important process in adult muscle stem cells
functions: it regulates metabolic reprogramming during activation from a quiescent state …

The beneficial effects of hair follicle stem cells in different animal models of nervous system
conditions have been extensively studied. While chick embryo extract (CEE) has been used …

In many leukemia patients, a poor prognosis is attributed either to the development of
chemotherapy resistance by leukemic stem cells (LSCs) or to the inefficient engraftment of …

Bone marrow mesenchymal stromal cells (BM-MSCs) are a rare population of cells that
gives rise to skeletal tissues and the hematopoietic stroma in vivo. Recently, we have …