Systemic osmoregulation is a vital process whereby changes in plasma osmolality, detected
by osmoreceptors, modulate ingestive behaviour, sympathetic outflow and renal function to …

Fitzsimons, JT Angiotensin, Thirst, and Sodium Appetite. Physiol. Rev. 78: 583–686, 1998.—
Angiotensin (ANG) II is a powerful and phylogenetically widespread stimulus to thirst and …

Osmotic homeostasis is one of the most aggressively defended physiological parameters in
vertebrates. However, the molecular mechanisms underlying osmotic regulation are poorly …

Relaxin has vital physiological roles in pregnant rats, mice, and pigs. Relaxin promotes
growth and softening of the cervix, thus facilitating rapid delivery of live young. Relaxin also …

Antunes-Rodrigues, José, Margaret de Castro, Lucila LK Elias, Marcelo M. Valença, and
Samuel M. McCann. Neuroendocrine Control of Body Fluid Metabolism. Physiol Rev 84: 169 …

The brain's three sensory circumventricular organs, the subfornical organ, organum
vasculosum of the lamina terminalis and the area postrema lack a blood brain barrier and …

The hypothalamo-neurohypophysial system (HNS) is the major peptidergic neurosecretory
system through which the brain controls peripheral physiology. The hormones vasopressin …

Located in the midline anterior wall of the third cerebral ventricle (ie the lamina terminalis),
the median preoptic nucleus (Mn PO) receives a unique set of afferent neural inputs from …

Magnocellular oxytocin and vasopressin cells are among the most extensively studied
neurons in the brain; their large size and high synthetic capacity, their discrete …

Circumventricular organs (CVO) play a critical role as transducers of information between
the blood, neurons and the cerebral spinal fluid (CSF). They permit both the release and …