Intelligent automated drug administration and therapy: future of healthcare

R Sharma, D Singh, P Gaur, D Joshi - Drug Delivery and Translational …, 2021 - Springer
In the twenty-first century, the collaboration of control engineering and the healthcare sector
has matured to some extent; however, the future will have promising opportunities, vast …

Solving an optimal control problem of cancer treatment by artificial neural networks

F Heydarpour, E Abbasi, MJ Ebadi, SM Karbassi - IJIMAI, 2020 - dialnet.unirioja.es
Cancer is an uncontrollable growth of abnormal cells in any tissue of the body. Many
researchers have focused on machine learning and artificial intelligence (AI) based on …

Derivation of an optimal trajectory and nonlinear adaptive controller design for drug delivery in cancerous tumor chemotherapy

P Khalili, R Vatankhah - Computers in biology and medicine, 2019 - Elsevier
Numerous models have investigated cancer behavior by considering different factors in
chemotherapy. The subject of a controller design approach for these models in order to find …

Experiment-based affect heuristic using fuzzy rules and Taguchi statistical method for tuning complex systems

NR Raz, MR Akbarzadeh-T, A Akbarzadeh - Expert Systems with …, 2021 - Elsevier
Affect heuristic is a subjective feeling that enables human's quick and efficient decision-
making in unstructured and uncertain environments. It is an experience-based subconscious …

Deep reinforcement learning control of combined chemotherapy and anti-angiogenic drug delivery for cancerous tumor treatment

VR Niazmand, MA Raheb, N Eqra, R Vatankhah… - Computers in Biology …, 2024 - Elsevier
By virtue of the chronic and dangerous nature of cancer, researchers have explored various
approaches to managing the abnormal cell growth associated with this disease using novel …

Adaptive boundary layer double integral sliding mode controller design for leukemia therapy

A Sengupta, DK Das - … Journal of Adaptive Control and Signal …, 2023 - Wiley Online Library
Presence of leukocytes in huge amount in the bone marrow and blood causes blood cancer
or leukemia. In leukemia, number of white blood corpuscles in blood increases rapidly …

Optimal control methods for drug delivery in cancerous tumour by anti‐angiogenic therapy and chemotherapy

P Khalili, S Zolatash, R Vatankhah… - IET Systems …, 2021 - Wiley Online Library
There are numerous mathematical models simulating the behaviour of cancer by
considering variety of states in different treatment strategies, such as chemotherapy. Among …

Design and implementation of an adaptive fuzzy sliding mode controller for drug delivery in treatment of vascular cancer tumours and its optimisation using genetic …

ES Ghasemabad, I Zamani, H Tourajizadeh… - IET Systems …, 2022 - Wiley Online Library
In this paper, the side effects of drug therapy in the process of cancer treatment are reduced
by designing two optimal non‐linear controllers. The related gains of the designed …

Design of adaptive super twisting tracking controllers for perturbed nonlinear systems with input constraints

CC Cheng, BY Chen, CC Wen - Nonlinear Dynamics, 2024 - Springer
This paper proposes an adaptive super-twisting control design method to solve tracking
problems for a class of perturbed MIMO nonlinear systems under the condition of input …

Optimal control of nonlinear fed-batch process using direct transcription method

A Simorgh, A Razminia, JAT Machado - Computers & Chemical …, 2019 - Elsevier
In this paper, we investigate the direct transcription method for dynamic optimization applied
to fed-batch processes. The performance index proposed for optimization has a more …