Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …

The flavonoids are polyphenolic compounds found as integral components of the human
diet. They are universally present as constituents of flowering plants, particularly of food …

Recent years have witnessed tremendous growth in the epidermal growth factor (EGF)
family of peptide growth factors and the ErbB family of tyrosine kinases, the receptors for …

Publisher Summary This chapter summarizes the recent knowledge on the production of
cytokines by neutrophils in vitro and in vivo—particularly molecular regulation and other …

Field cancerization predisposes the upper aerodigestive tract mucosa to the formation of
multiple primary tumors, when exposed to environmental carcinogens. Up-regulation of …

Stimulation of epidermal growth factor receptor (EGFR) by ligand (s) leads to activation of
signaling molecules including Stat1 and Stat3, two members of the signal transducers and …

In addition to acting as a physical barrier against microorganisms, the skin produces
antimicrobial peptides and proteins. After wounding, growth factors are produced to …

It has become well accepted that solid tumors must create a vascular system for nutrient
delivery and waste removal in order to grow appreciably. This process, angiogenesis, is …

The choice of study population needs to be carefully considered for studies of markers of
potential prognostic importance. Many published studies include patients with all Dukes' …

Compiling significant advances from more than a decade of research, this text presents
breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …