The caspase family of cysteine proteases represents the executioners of programmed cell
death (PCD) type I or apoptosis. For years, caspases have been known for their critical roles …

Ultrafast 3D imaging is indispensable for visualizing complex and dynamic biological
processes. Conventional scanning-based techniques necessitate an inherent trade-off …

Here we highlight the increasingly divergent functions of the Caenorhabditis elegans cell
elimination genes in the nervous system, beyond their well-documented roles in cell …

In the aging brain, many of the alterations underlying cognitive and behavioral decline
remain opaque. Caenorhabditis elegans offers a powerful model for aging research, with a …

The heteroplasmic state of eukaryotic cells allows for cryptic accumulation of defective
mitochondrial genomes (mtDNA).'Purifying selection'mechanisms operate to remove such …

Despite being integral to the practice of surgery, the mechanisms by which general
anesthetics mediate their effects remain unknown. For this reason, it is difficult to predict …

Organismal development relies on precise temporal and spatial regulation of numerous
processes to ensure proper formation of the body plan including the enforcement of …