Cholecystokinin (CCK) regulation of pancreatic acinar cells: physiological actions and signal transduction mechanisms

JA Williams - Comprehensive Physiology, 2011 - Wiley Online Library
Pancreatic acinar cells synthesize and secrete about 20 digestive enzymes and ancillary
proteins with the processes that match the supply of these enzymes to their need in …

[HTML][HTML] Differential regulation of ion channels function by proteolysis

L Wang, DI Yule - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2018 - Elsevier
Ion channels are pore-forming protein complexes in membranes that play essential roles in
a diverse array of biological activities. Ion channel activity is strictly regulated at multiple …

[HTML][HTML] Region-specific proteolysis differentially modulates type 2 and type 3 inositol 1, 4, 5-trisphosphate receptor activity in models of acute pancreatitis

L Wang, LE Wagner, KJ Alzayady, DI Yule - Journal of Biological Chemistry, 2018 - ASBMB
Fine-tuning of the activity of inositol 1, 4, 5-trisphosphate receptors (IP 3 R) by a diverse
array of regulatory inputs results in intracellular Ca 2+ signals with distinct characteristics …