Background There are various reasons why weaning and extubation failure occur, but
ineffective cough and secretion retention can play a significant role. Cough augmentation …

Purpose Much of the common practice in paediatric mechanical ventilation is based on
personal experiences and what paediatric critical care practitioners have adopted from adult …

Respiratory muscle weakness is a major cause of morbidity and mortality in patients with
neuromuscular diseases (NMDs). Respiratory involvement in NMDs can manifest broadly …

Mechanical insufflation-exsufflation (MI-E) is a strategy to treat pulmonary exacerbations in
neuromuscular disorders (NMDs). Pediatric guidelines for optimal setting titration of MI-E are …

Background: To determine the effectiveness of combined noninvasive ventilation (NIV) and
mechanical insufflator-exsufflator (MI-E) for acute respiratory failure (ARF) in patients with …

Introduction Spinal muscular atrophy (SMA) is caused by a defect in the survival motor
neuron 1 (SMN1) gene. The Cooperative Study of the natural history of SMA Type I in …

Neuromuscular disorders (NMDs) may be associated with a gradual loss of muscle function
over time, and children with these disorders are at risk of developing clinically significant …

Non-Invasive respiratory support can be viewed as mechanical respiratory support without
endotracheal intubation and it includes continuous positive airway pressure, bi-level positive …

Children with neuromuscular disorder (NMD) usually have pulmonary involvement
characterized by weakened respiratory muscles, insufficient coughing, and inability to clear …

Non‐invasive ventilation (NIV) is commonly used in paediatric intensive care units (PICU s)
for respiratory failure. This review aims to improve paediatricians' understanding of NIV, by …