Decreased aperiodic neural activity in Parkinson's disease and dementia with Lewy bodies

Y Rosenblum, T Shiner, N Bregman, N Giladi… - Journal of …, 2023 - Springer
Neural oscillations and signal complexity have been widely studied in neurodegenerative
diseases, whereas aperiodic activity has not been explored yet in those disorders. Here, we …

The selfish network: how the brain preserves behavioral function through shifts in neuronal network state

A Stroh, S Schweiger, JM Ramirez, O Tüscher - Trends in Neurosciences, 2024 - cell.com
Neuronal networks possess the ability to regulate their activity states in response to
disruptions. How and when neuronal networks turn from physiological into pathological …

Alterations of Cortical Structure and Neurophysiology in Parkinson's Disease Are Aligned with Neurochemical Systems

AI Wiesman, J da Silva Castanheira, EA Fon… - Annals of …, 2024 - Wiley Online Library
Objective Parkinson's disease (PD) affects the structural integrity and neurophysiological
signaling of the cortex. These alterations are related to the motor and cognitive symptoms of …

Oscillatory and non-oscillatory features of the magnetoencephalic sensorimotor rhythm in Parkinson's disease

MC Vinding, J Waldthaler, A Eriksson… - npj Parkinson's …, 2024 - nature.com
Parkinson's disease (PD) is associated with changes in neural activity in the sensorimotor
alpha and beta bands. Using magnetoencephalography (MEG), we investigated the role of …

Electroencephalogram rhythmic and arrhythmic spectral components and functional connectivity at resting state may predict the development of synucleinopathies in …

J Hernandez, JM Lina, J Dubé, A Lafrenière… - Sleep, 2024 - academic.oup.com
Abstract Study Objectives Idiopathic/isolated rapid eye movement-sleep behavior disorder
(iRBD) often precedes the onset of synucleinopathies. Here, we investigated whether …

Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease

AI Wiesman, V Madge, EA Fon, A Dagher, DL Collins… - Brain, 2024 - academic.oup.com
Parkinson's disease (PD) is marked by the death of neuromelanin-rich dopaminergic and
noradrenergic cells in the substantia nigra (SN) and the locus coeruleus (LC), respectively …

Spectral Slope and Lempel–Ziv Complexity as Robust Markers of Brain States during Sleep and Wakefulness

C Höhn, MA Hahn, JD Lendner, K Hoedlmoser - Eneuro, 2024 - eneuro.org
Nonoscillatory measures of brain activity such as the spectral slope and Lempel–Ziv
complexity are affected by many neurological disorders and modulated by sleep. A multitude …

Changes in electrophysiological aperiodic activity during cognitive control in Parkinson's disease

N Monchy, J Modolo, JF Houvenaghel… - Brain …, 2024 - academic.oup.com
Cognitive symptoms in Parkinson's disease are common and can significantly affect patients'
quality of life. Therefore, there is an urgent clinical need to identify a signature derived from …

Human sensorimotor beta event characteristics and aperiodic signal are highly heritable

KAM Pauls, E Salmela, O Korsun, J Kujala… - Journal of …, 2024 - Soc Neuroscience
Individuals' phenotypes, including the brain's structure and function, are largely determined
by genes and their interplay. The resting brain generates salient rhythmic patterns that can …

Differentiating neurodegenerative diseases based on EEG complexity

G Mostile, R Terranova, G Carlentini, F Contrafatto… - Scientific Reports, 2024 - nature.com
Neurodegenerative diseases are common causes of impaired mobility and cognition in the
elderly. Among them, tauopathies and α-synucleinopathies were considered. The …