Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

In the search for new sources of antimicrobials many researchers have investigated
antimicrobial peptides (AMPs) as templates for the design of innovative therapeutics …

Sequence-defined peptoids, or N-substituted glycines, are an attractive class of bioispired
polymer due to their biostability and efficient synthesis. However, the de novo design of …

Peptoids are oligomers of N‐substituted glycine units. They structurally resemble peptides
but, unlike natural peptides, the side chains of peptoids are present on the amide nitrogen …

Peptides have been heavily investigated for their biocompatible and bioactive properties.
Though a wide array of functionalities can be introduced by varying the amino acid …

The use of hydrazones as a new type of submonomer in peptoid synthesis is described,
giving access to peptoid monomers that are structure-inducing. A wide range of hydrazones …

Peptoids are peptidomimetics of interest in the fields of drug development and biomaterials.
However, obtaining stable secondary structures is challenging, and designing these …

The development and the use of fluorinated polyproline-type II (PPII) foldamers are still
underexplored. Herein, trifluoromethyl pseudoprolines have been incorporated into …

Controlling the network of intramolecular interactions encoded by N α-chiral side chains and
the equilibria between cis-and trans-amide junctions in cyclic peptoid architectures …

Combinatorial chemistry allows for the rapid synthesis of large compound libraries for high
throughput screenings in biology, medicinal chemistry, or materials science. Especially …