Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential

L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Fluorescent probes for biological species and microenvironments: from rational design to bioimaging applications

H Fang, Y Chen, Z Jiang, W He… - Accounts of chemical …, 2023 - ACS Publications
Conspectus Some important biological species and microenvironments maintain a complex
and delicate dynamic balance in life systems, participating in the regulation of various …

Fluorescent probes for organelle-targeted bioactive species imaging

P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …

Fluorescent sensors for measuring metal ions in living systems

KP Carter, AM Young, AE Palmer - Chemical reviews, 2014 - ACS Publications
All life forms have an absolute requirement for metals, as metals play critical roles in
fundamental processes, including osmotic regulation, catalysis, metabolism …

Development of ion chemosensors based on porphyrin analogues

Y Ding, WH Zhu, Y Xie - Chemical Reviews, 2017 - ACS Publications
Sensing of metal ions and anions is of great importance because of their widespread
distribution in environmental systems and biological processes. Colorimetric and fluorescent …

Noninvasive and Spatiotemporal Control of DNAzyme-Based Imaging of Metal Ions In Vivo Using High-Intensity Focused Ultrasound

X Wang, G Kim, JL Chu, T Song, Z Yang… - Journal of the …, 2022 - ACS Publications
Detecting metal ions in vivo with a high spatiotemporal resolution is critical to understanding
the roles of the metal ions in both healthy and disease states. Although spatiotemporal …

Mitochondria‐targeted cancer therapy using a light‐up probe with aggregation‐induced‐emission characteristics

Q Hu, M Gao, G Feng, B Liu - … Chemie International Edition, 2014 - Wiley Online Library
Subcellular organelle‐specific reagents for simultaneous tumor targeting, imaging, and
treatment are of enormous interest in cancer therapy. Herein, we present a mitochondria …

Optical control of metal ion probes in cells and zebrafish using highly selective DNAzymes conjugated to upconversion nanoparticles

Z Yang, KY Loh, YT Chu, R Feng… - Journal of the …, 2018 - ACS Publications
Spatial and temporal distributions of metal ions in vitro and in vivo are crucial in our
understanding of the roles of metal ions in biological systems, and yet there is a very limited …

Fluorescence imaging of metal ions implicated in diseases

X Qian, Z Xu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal ions play an important role in various biological processes, their abnormal
homeostasis in cells is related to many diseases, such as neurodegenerative disease …

[HTML][HTML] Toxic effects and toxicological mechanisms of chlorinated paraffins: A review for insight into species sensitivity and toxicity difference

S Chen, Y Gong, Y Luo, R Cao, J Yang, L Cheng… - Environment …, 2023 - Elsevier
Chlorinated paraffins (CPs), a group of chlorinated alkane mixtures, are frequently detected
in various environmental matrices and human bodies. Recently, CPs have garnered …