Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Medicinal plants in the treatment of depression: Evidence from preclinical studies

I Moragrega, JL Ríos - Planta medica, 2021 - thieme-connect.com
Medicinal plants and their extracts are natural remedies with enormous potential for treating
various diseases, including depression and anxiety. In the case of depression, hundreds of …

Plant-derived natural medicines for the management of depression: an overview of mechanisms of action

MS Farahani, R Bahramsoltani, MH Farzaei… - Reviews in the …, 2015 - degruyter.com
Depression is a serious widespread psychiatric disorder that affects approximately 17% of
people all over the world. Exploring the neurological mechanisms of the antidepressant …

Antidepressant-Like Behavioral, Anatomical, and Biochemical Effects of Petroleum Ether Extract from Maca (Lepidium meyenii) in Mice Exposed to Chronic …

Z Ai, AF Cheng, YT Yu, LJ Yu, W Jin - Journal of medicinal food, 2014 - liebertpub.com
Maca has been consumed as a medical food in Peru for thousands of years, and exerts
anxiolytic and antidepressant effects. Our present study aimed to evaluate the behavior and …

Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba)

NO Martins, IM De Brito, SSO Araújo, G Negri… - … and alternative medicine, 2018 - Springer
Abstract Background Trichilia catigua A. Juss.(Meliaceae) is a species known as catuaba
and used in folk medicine for the treatment of fatigue, stress, impotence and memory deficit …

Trichilia catigua (Catuaba) bark extract exerts neuroprotection against oxidative stress induced by different neurotoxic agents in rat hippocampal slices

JP Kamdem, EO Olalekan, W Hassan, IJ Kade… - Industrial Crops and …, 2013 - Elsevier
Plant extracts have been reported to prevent various diseases associated with oxidative
stress. Trichilia catigua, a traditional Brazilian herbal medicine, exhibits beneficial …

[HTML][HTML] Ethyl-acetate fraction of Trichilia catigua protects against oxidative stress and neuroinflammation after cerebral ischemia/reperfusion

J Godinho, AB de Sa-Nakanishi, LS Moreira… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Trichilia catigua A. Juss (Meliaceae) preparations have
been used in folk medicine to alleviate fatigue, stress, and improve memory. Antinociceptive …

[HTML][HTML] Trichilia catigua: therapeutic and cosmetic values

R Longhini, AASG Lonni, AL Sereia… - Revista Brasileira de …, 2017 - SciELO Brasil
Medicinal plants play an important role in human health care. It is estimated that about 25–
30% of all drugs are evaluated as therapeutic agents derived from natural products …

[HTML][HTML] Anti-diabetic effects of the ethyl-acetate fraction of Trichilia catigua in streptozo-tocin-induced type 1 diabetic rats

RM Gomes, LF de Paulo… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Trichilia catigua A. Juss., known as “catuaba” in Brazil, has been
popularly used as a tonic for fatigue, impotence and memory deficits. Previously, our group …

Ethyl-acetate fraction of Trichilia catigua restores long-term retrograde memory and reduces oxidative stress and inflammation after global cerebral ischemia in rats

J Godinho, RMW de Oliveira… - Behavioural brain …, 2018 - Elsevier
We originally reported that an ethyl-acetate fraction (EAF) of Trichilia catigua prevented the
impairment of water maze learning and hippocampal neurodegeneration after transient …