▪ Abstract The initial step in olfactory discrimination involves the interaction of odorous
ligands with specific receptors on the surface of olfactory sensory neurons. The foundation …

While the significance of middle repetitive elements had been neglected for a long time,
there are again tendencies to ascribe most members of a given middle repetitive sequence …

Olfactory receptors likely constitute the largest gene superfamily in the vertebrate genome.
Here we present the nearly complete human olfactory subgenome elucidated by mining the …

Olfactory receptors (ORs) located in the cell membrane of olfactory sensory neurons of the
nasal epithelium are responsible for odor detection by binding specific odorant ligands …

Here, we provide the first evidence for functional expression of a human olfactory receptor
protein (OR17–40) and show that recombinant olfactory receptors can be functionally …

3. Anatomy of the mammalian olfactory system 3.1. Olfactory epithelium; a sheet of olfactory
sensory neurons 3.2. Olfactory bulb; the first relay station in the central olfactory system 4 …

A novel receptor cDNA was isolated from a human hippocampal cDNA library. The encoded
polypeptide contains structural features consistent with its classification as a G protein …

We demonstrate that members of the olfactory receptor (OR) gene family are distributed on
all but a few human chromosomes. Through FISH analysis, we show that OR sequences …

Olfactory receptors constitute a huge family of structurally related G protein-coupled
receptors, with up to a thousand members expected. We have shown previously that genes …

A gene superfamily of olfactory receptors (ORs) has recently been identified in a number of
species. These receptors share a seven transmembrane domain structure with many …