To date, a large number of mutations in SCN5A, the gene encoding the pore-forming α-
subunit of the primary cardiac Na+ channel (NaV1. 5), have been found in patients …

An alternative analgesic to morphine is methadone, which is used to control chronic pain
and is used in opioid rehabilitation treatment programs due to methadone having a long half …

Abstract Background Brugada syndrome (Brs) and long QT syndrome (LQTs) are the most
observed “inherited primary arrhythmia syndromes” and “channelopathies”, which lead to …

Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) are now
a well-established modality for modeling genetic disorders of the heart. This is especially so …

Sudden infant death syndrome (SIDS) is the unexpected death of an infant under one year
of age that remains unexplained after a thorough investigation. Despite SIDS remaining a …

The two primary classes of opioid substances are morphine and its synthetic derivative,
heroin. Opioids can cross the placental barrier, reaching fetal circulation. Therefore, at any …

The mechanism of death in Sudden infant death syndrome (SIDS) remains unknown but it is
hypothesised that cardiorespiratory failure of brainstem origin results in early post-natal …

(1) Background: Sudden Infant Death Syndrome (SIDS) represents sudden and unexplained
deaths during the sleep of infants under one year of age, despite thorough investigation …

La definición del Síndrome de Muerte Súbita del Lactante (SMSL) es la muerte inesperada
de un niño antes de los 12meses durante el sueño ya la que no se le encuentra unacausa …

Background Abnormal prolongation in the QT interval or long QT syndrome (LQTS) is
associated with several cardiac complications such as sudden infant death syndrome …