Consciousness and sleep

G Tononi, M Boly, C Cirelli - Neuron, 2024 - cell.com
Sleep is a universal, essential biological process. It is also an invaluable window on
consciousness. It tells us that consciousness can be lost but also that it can be regained, in …

Neurosteroids foster sedation by engaging tonic GABAA-Rs within the mesopontine tegmental anesthesia area (MPTA)

M Baron, M Devor - Neuroscience Letters, 2024 - Elsevier
Neurosteroids are endogenous molecules with anxiolytic, anticonvulsant, sleep-promoting
and sedative effects. They are biosynthesized de novo within the brain, among other tissues …

Central nucleus of the amygdala to medial prefrontal cortex 5-HTergic neural circuit modulates the recovery of consciousness during sevoflurane anesthesia

YL Wang, Y Yang, YX Wu, XX Xu, Q Xu, ZW Zhang… - bioRxiv, 2024 - biorxiv.org
General anesthesia, widely employed for its capacity to induce unconsciousness during
surgical and diagnostic procedures, frequently results in postoperative recovery delays, a …

The Putative Role of the Medial Prefrontal Cortex in Emergence from General Anesthesia

E Huels - 2024 - deepblue.lib.umich.edu
Studies over the past century have yielded abundant data to support a clear role for
subcortical structures in regulating states of arousal such as sleep, wake, and anesthesia …