Molecular cogs: interplay between circadian clock and cell cycle
The cell cycle and the circadian clock operate as biological oscillators whose timed
functions are tightly regulated. Accumulating evidence illustrates the presence of molecular …
functions are tightly regulated. Accumulating evidence illustrates the presence of molecular …
Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression
M Valdés‐Tovar, R Estrada‐Reyes… - British journal of …, 2018 - Wiley Online Library
Mood disorders are a spectrum of neuropsychiatric disorders characterized by changes in
the emotional state. In particular, major depressive disorder is expected to have a worldwide …
the emotional state. In particular, major depressive disorder is expected to have a worldwide …
[HTML][HTML] Adult neurogenesis: A story ranging from controversial new neurogenic areas and human adult neurogenesis to molecular regulation
P Leal-Galicia, ME Chávez-Hernández, F Mata… - International journal of …, 2021 - mdpi.com
The generation of new neurons in the adult brain is a currently accepted phenomenon. Over
the past few decades, the subventricular zone and the hippocampal dentate gyrus have …
the past few decades, the subventricular zone and the hippocampal dentate gyrus have …
Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights
PP Zheng, J Li, JM Kros - Medicinal research reviews, 2018 - Wiley Online Library
To date, five cancer treatment modalities have been defined. The three traditional modalities
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …
[HTML][HTML] Melatonin as a harmonizing factor of circadian rhythms, neuronal cell cycle and neurogenesis: additional arguments for its therapeutic use in Alzheimer's …
M Shukla, B Vincent - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
The synthesis and release of melatonin in the brain harmonize various physiological
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …
[HTML][HTML] Circadian clock, time-restricted feeding and reproduction
The goal of this review was to seek a better understanding of the function and differential
expression of circadian clock genes during the reproductive process. Through a discussion …
expression of circadian clock genes during the reproductive process. Through a discussion …
[HTML][HTML] Ticking time bombs: connections between circadian clocks and cancer
KA Lamia - F1000Research, 2017 - ncbi.nlm.nih.gov
Connections between mammalian circadian and cell division cycles have been postulated
since the early 20th century, and epidemiological and genetic studies have linked disruption …
since the early 20th century, and epidemiological and genetic studies have linked disruption …
[HTML][HTML] The cancer clock is (not) ticking: links between circadian rhythms and cancer
MN Morgan, S Dvuchbabny, CA Martinez, B Kerr… - Clocks & sleep, 2019 - mdpi.com
Circadian rhythms regulate many physiological and behavioral processes, including sleep,
metabolism and cell division, which have a 24-h oscillation pattern. Rhythmicity is generated …
metabolism and cell division, which have a 24-h oscillation pattern. Rhythmicity is generated …
[HTML][HTML] The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar
FM Conedera, AMQ Pousa, N Mercader… - Molecular …, 2021 - Springer
Background Contrasting with zebrafish, retinal regeneration from Müller cells (MCs) is
largely limited in mammals, where they undergo reactive gliosis that consist of a …
largely limited in mammals, where they undergo reactive gliosis that consist of a …
Rnaseq analysis of brain aging in wild specimens of short-lived turquoise killifish: Commonalities and differences with aging under laboratory conditions
M Mazzetto, C Caterino, M Groth… - Molecular Biology …, 2022 - academic.oup.com
A vast body of studies is available that describe age-dependent gene expression in relation
to aging in a number of different model species. These data were obtained from animals …
to aging in a number of different model species. These data were obtained from animals …