Molecular cogs: interplay between circadian clock and cell cycle

J Gaucher, E Montellier, P Sassone-Corsi - Trends in Cell Biology, 2018 - cell.com
The cell cycle and the circadian clock operate as biological oscillators whose timed
functions are tightly regulated. Accumulating evidence illustrates the presence of molecular …

Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression

M Valdés‐Tovar, R Estrada‐Reyes… - British journal of …, 2018 - Wiley Online Library
Mood disorders are a spectrum of neuropsychiatric disorders characterized by changes in
the emotional state. In particular, major depressive disorder is expected to have a worldwide …

[HTML][HTML] Adult neurogenesis: A story ranging from controversial new neurogenic areas and human adult neurogenesis to molecular regulation

P Leal-Galicia, ME Chávez-Hernández, F Mata… - International journal of …, 2021 - mdpi.com
The generation of new neurons in the adult brain is a currently accepted phenomenon. Over
the past few decades, the subventricular zone and the hippocampal dentate gyrus have …

Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights

PP Zheng, J Li, JM Kros - Medicinal research reviews, 2018 - Wiley Online Library
To date, five cancer treatment modalities have been defined. The three traditional modalities
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …

[HTML][HTML] Melatonin as a harmonizing factor of circadian rhythms, neuronal cell cycle and neurogenesis: additional arguments for its therapeutic use in Alzheimer's …

M Shukla, B Vincent - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
The synthesis and release of melatonin in the brain harmonize various physiological
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …

[HTML][HTML] Circadian clock, time-restricted feeding and reproduction

X Pan, MJ Taylor, E Cohen, N Hanna… - International journal of …, 2020 - mdpi.com
The goal of this review was to seek a better understanding of the function and differential
expression of circadian clock genes during the reproductive process. Through a discussion …

[HTML][HTML] Ticking time bombs: connections between circadian clocks and cancer

KA Lamia - F1000Research, 2017 - ncbi.nlm.nih.gov
Connections between mammalian circadian and cell division cycles have been postulated
since the early 20th century, and epidemiological and genetic studies have linked disruption …

[HTML][HTML] The cancer clock is (not) ticking: links between circadian rhythms and cancer

MN Morgan, S Dvuchbabny, CA Martinez, B Kerr… - Clocks & sleep, 2019 - mdpi.com
Circadian rhythms regulate many physiological and behavioral processes, including sleep,
metabolism and cell division, which have a 24-h oscillation pattern. Rhythmicity is generated …

[HTML][HTML] The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar

FM Conedera, AMQ Pousa, N Mercader… - Molecular …, 2021 - Springer
Background Contrasting with zebrafish, retinal regeneration from Müller cells (MCs) is
largely limited in mammals, where they undergo reactive gliosis that consist of a …

Rnaseq analysis of brain aging in wild specimens of short-lived turquoise killifish: Commonalities and differences with aging under laboratory conditions

M Mazzetto, C Caterino, M Groth… - Molecular Biology …, 2022 - academic.oup.com
A vast body of studies is available that describe age-dependent gene expression in relation
to aging in a number of different model species. These data were obtained from animals …