Poly (ADP-ribose) polymerase-1 cleavage during apoptosis: an update

C Soldani, AI Scovassi - Apoptosis, 2002 - Springer
Poly (ADP-ribosylation) is a post-translational modification of proteins playing a crucial role
in many processes, including DNA repair and cell death. The best known poly (ADP …

Nuclear apoptotic changes: an overview

AM Martelli, M Zweyer, RL Ochs… - Journal of cellular …, 2001 - Wiley Online Library
Apoptosis is a form of active cell death essential for morphogenesis, development,
differentiation, and homeostasis of multicellular organisms. The activation of genetically …

Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa

Y Meng, W Tang, Y Dai, X Wu, M Liu, Q Ji, M Ji… - Molecular cancer …, 2008 - AACR
Antiapoptotic members of the Bcl-2 family proteins are overexpressed in prostate cancer and
are promising molecular targets for modulating chemoresistance of prostate cancer.(-) …

Poly (ADP-ribose) polymerase cleavage during apoptosis: when and where?

C Soldani, MC Lazzè, MG Bottone, G Tognon… - Experimental cell …, 2001 - Elsevier
Poly (ADP-ribose) polymerase-1 (PARP-1) plays the active role of “nick sensor” during DNA
repair and apoptosis, when it synthesizes ADP-ribose from NAD+ in the presence of DNA …

Apoptotic cell clearance in systemic lupus erythematosus: I. Opsonization by antiphospholipid antibodies

AA Manfredi, P Rovere, G Galati… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To verify whether antiphospholipid antibodies (aPL) recognize and opsonize
apoptotic human cells. Methods Apoptosis was induced via CD95 crosslinking or ultraviolet …

Apoptotic tumor cell-derived extracellular vesicles as important regulators of the onco-regenerative niche

CD Gregory, I Dransfield - Frontiers in immunology, 2018 - frontiersin.org
Cells undergoing apoptosis produce heterogeneous populations of membrane delimited
extracellular vesicles (Apo-EVs) which vary not only in size—from tens of nanometers to …

Morphological features of organelles during apoptosis: an overview

MG Bottone, G Santin, F Aredia, G Bernocchi… - Cells, 2013 - mdpi.com
An apoptotic program leading to controlled cell dismantling implies perturbations of nuclear
dynamics, as well as changes affecting the organelle structure and distribution. In human …

Nuclear patterns of human breast cancer cells during apoptosis: characterisation by fractal dimension and co-occurrence matrix statistics

GA Losa, C Castelli - Cell and tissue research, 2005 - Springer
An analytical strategy combining fractal geometry and grey-level co-occurrence matrix
(GLCM) statistics was devised to investigate ultrastructural changes in oestrogen-insensitive …

Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission

SM Markert, M Skoruppa, B Yu, B Mulcahy… - Biology …, 2020 - journals.biologists.com
The amyotrophic lateral sclerosis (ALS) neurodegenerative disorder has been associated
with multiple genetic lesions, including mutations in the gene for fused in sarcoma (FUS), a …

Rearrangement of nuclear ribonucleoprotein (RNP)-containing structures during apoptosis and transcriptional arrest

M Biggiogera, MG Bottone, AI Scovassi, C Soldani… - Biology of the Cell, 2004 - Elsevier
The aim of this paper is to review the data in the literature concerning ribonucleoprotein
components during apoptosis, where a major rearrangement of RNPs takes place. In …