COVID-19-associated fungal infections
Abstract Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an
important complication in a substantial number of critically ill, hospitalized patients with …
important complication in a substantial number of critically ill, hospitalized patients with …
Sepsis-induced immunosuppression
LK Torres, P Pickkers… - Annual review of …, 2022 - annualreviews.org
Sepsis is expected to have a substantial impact on public health and cost as its prevalence
increases. Factors contributing to increased prevalence include a progressively aging …
increases. Factors contributing to increased prevalence include a progressively aging …
[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review
B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …
host response to infection. In sepsis, the immune response that is initiated by an invading …
Advances in the understanding and treatment of sepsis-induced immunosuppression
F Venet, G Monneret - Nature Reviews Nephrology, 2018 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. Sepsis can induce acute kidney injury and multiple organ failures …
host response to infection. Sepsis can induce acute kidney injury and multiple organ failures …
Interferon-gamma (IFN-γ): Exploring its implications in infectious diseases
A key player in driving cellular immunity, IFN-γ is capable of orchestrating numerous
protective functions to heighten immune responses in infections and cancers. It can exhibit …
protective functions to heighten immune responses in infections and cancers. It can exhibit …
[HTML][HTML] Host-directed therapies for bacterial and viral infections
SHE Kaufmann, A Dorhoi, RS Hotchkiss… - Nature reviews Drug …, 2018 - nature.com
Despite the recent increase in the development of antivirals and antibiotics, antimicrobial
resistance and the lack of broad-spectrum virus-targeting drugs are still important issues and …
resistance and the lack of broad-spectrum virus-targeting drugs are still important issues and …
Aspergillus fumigatus morphology and dynamic host interactions
FL Van De Veerdonk, MS Gresnigt, L Romani… - Nature Reviews …, 2017 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …
disease in immunocompromised individuals. The interactions between A. fumigatus and the …
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
The acute phase of sepsis is characterized by a strong inflammatory reaction. At later stages
in some patients, immunoparalysis may be encountered, which is associated with a poor …
in some patients, immunoparalysis may be encountered, which is associated with a poor …
Immune defence against Candida fungal infections
MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …