[HTML][HTML] Synthetic cathinone and cannabinoid designer drugs pose a major risk for public health

AM Weinstein, P Rosca, L Fattore… - Frontiers in psychiatry, 2017 - frontiersin.org
As part of an increasing worldwide use of designer drugs, recent use of compounds
containing cathinones and synthetic cannabinoids is especially prevalent. Here, we …

Intracranial self-stimulation to evaluate abuse potential of drugs

SS Negus, LL Miller - Pharmacological reviews, 2014 - ASPET
Intracranial self-stimulation (ICSS) is a behavioral procedure in which operant responding is
maintained by pulses of electrical brain stimulation. In research to study abuse-related drug …

Abuse potential and toxicity of the synthetic cathinones (ie,“Bath salts”)

AL Riley, KH Nelson, P To, R López-Arnau, P Xu… - Neuroscience & …, 2020 - Elsevier
The synthetic cathinones are derived from the naturally occurring drug cathinone found in
the khat plant (Catha edulis) and have chemical structures and neurochemical …

[HTML][HTML] Neuropharmacology of new psychoactive substances (NPS): focus on the rewarding and reinforcing properties of cannabimimetics and amphetamine-like …

C Miliano, G Serpelloni, C Rimondo, M Mereu… - Frontiers in …, 2016 - frontiersin.org
New psychoactive substances (NPS) are a heterogeneous and rapidly evolving class of
molecules available on the global illicit drug market (eg smart shops, internet,“dark net”) as a …

Neuropharmacology of synthetic cathinones

MH Baumann, HM Walters, M Niello… - … , Clinical, Forensic and …, 2018 - Springer
Synthetic cathinones are derivatives of the naturally occurring compound cathinone, the
main psychoactive ingredient in the khat plant Catha edulis. Cathinone is the β-keto analog …

Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone …

CW Schindler, EB Thorndike, SR Goldberg… - …, 2016 - Springer
Abstract Rationale 3, 4-Methylenedioxypyrovalerone (MDPV) and 3, 4-methylenedioxy-N-
methylcathinone (methylone) are synthetic drugs found in so-called “bath salts” products …

Neurobiology of 3, 4-methylenedioxypyrovalerone (MDPV) and α-pyrrolidinovalerophenone (α-PVP)

RA Glennon, R Young - Brain research bulletin, 2016 - Elsevier
Synthetic cathinones are analogs of cathinone or β-ketoamphetamine–the major
psychostimulant component of the shrub Catha edulis or khat. Cathinone analogs–though …

Intravenous self-administration of mephedrone, methylone and MDMA in female rats

KM Creehan, SA Vandewater, MA Taffe - Neuropharmacology, 2015 - Elsevier
Male rats will intravenously self-administer (IVSA) the substituted cathinone stimulants (“bath
salts”) mephedrone (4-methylmethcathione) and methylone (3, 4 …

[HTML][HTML] 'Second-generation'mephedrone analogs, 4-MEC and 4-MePPP, differentially affect monoamine transporter function

K Saha, JS Partilla, KR Lehner, A Seddik… - …, 2015 - nature.com
The nonmedical use of synthetic cathinones is increasing on a global scale. 4-Methyl-N-
methylcathinone (mephedrone) is a popular synthetic cathinone that is now illegal in the …

Neuropharmacology of 3, 4-methylenedioxypyrovalerone (MDPV), its metabolites, and related analogs

MH Baumann, MO Bukhari, KR Lehner… - … of New Psychoactive …, 2017 - Springer
Methylenedioxypyrovalerone (MDPV) is a psychoactive component of so-called bath salts
products that has caused serious medical consequences in humans. In this chapter, we …