The NLRP3 inflammasome: a potential therapeutic target for traumatic brain injury

S Ismael, HA Ahmed, T Adris, K Parveen… - Neural regeneration …, 2021 - journals.lww.com
Although the precise mechanisms contributing to secondary brain injury following traumatic
brain injury are complex and obscure, a number of studies have demonstrated that …

Hyperbaric oxygen therapy: A new look on treating stroke and traumatic brain injury

B Gonzales-Portillo, T Lippert, H Nguyen, JY Lee… - Brain …, 2019 - journals.lww.com
Although hyperbaric oxygen therapy (HBOT) is common as a treatment for injuries, this study
aimed to research the ability of HBOT in preconditioning to diminish any potential damage …

Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondria transfer

T Lippert, CV Borlongan - CNS neuroscience & therapeutics, 2019 - Wiley Online Library
Aims Hyperbaric oxygen therapy (HBOT) has been widely used as postinjury treatment;
however, we investigate its ability to mitigate potential damage as a preconditioning option …

The complexity of secondary cascade consequent to traumatic brain injury: pathobiology and potential treatments

N Khatri, B Sumadhura, S Kumar… - Current …, 2021 - benthamdirect.com
According to the World Health Organization, Traumatic brain injury (TBI) is the major cause
of death and disability and will surpass the other diseases by the year 2020. Patients who …

Aqueous Grown Quantum Dots with Robust Near-Infrared Fluorescence for Integrated Traumatic Brain Injury Diagnosis and Surgical Monitoring

M Jiao, X Li, H Liu, P Cai, X Yang, KJ McHugh… - ACS …, 2024 - ACS Publications
Surgical intervention is the most common first-line treatment for severe traumatic brain
injuries (TBIs) associated with high intracranial pressure, while the complexity of these …

Impact of early nutrition and feeding route on clinical outcomes of neurocritically ill patients

YK Choi, HJ Kim, J Ahn, JA Ryu - Plos one, 2023 - journals.plos.org
Early proper nutritional support is important to critically ill patients. Nutritional support is also
associated with clinical outcomes of neurocritically ill patients. We investigate whether early …

The role of gaseous molecules in traumatic brain injury: an updated review

X Che, Y Fang, X Si, J Wang, X Hu, C Reis… - Frontiers in …, 2018 - frontiersin.org
Traumatic brain injury (TBI) affects millions of people in China each year. TBI has a high
mortality and often times a serious prognosis. The causative mechanisms of TBI during …

Significance of cerebrospinal fluid inflammatory markers for diagnosing external ventricular drain–associated ventriculitis in patients with severe traumatic brain injury

M Lenski, A Biczok, K Neufischer, JC Tonn… - Neurosurgical …, 2019 - thejns.org
Objective The aim of this study was to investigate the diagnostic potential of the inflammatory
markers interleukin-6 (IL-6), total leukocyte count (TLC), and protein in the CSF and IL-6, C …

[HTML][HTML] Mechanical behaviour of composite calcium phosphate–titanium cranial implants: Effects of loading rate and design

S Lewin, J Åberg, D Neuhaus, H Engqvist… - journal of the …, 2020 - Elsevier
Cranial implants are used to repair bone defects following neurosurgery or trauma. At
present, there is a lack of data on their mechanical response, particularly in impact loading …

The 'Omics' of epigenetic modulation by valproic acid treatment in traumatic brain injury—what we know and what the future holds

UF Bhatti, AM Williams, PE Georgoff… - PROTEOMICS …, 2019 - Wiley Online Library
Traumatic brain injury (TBI) is a heterogeneous injury that is a major cause of morbidity and
mortality worldwide. Epigenetic modulation through the alteration of cellular acetylation by …