The p38 mitogen-activated kinase (MAPK) family controls cell adaptation to stress stimuli.
p38 function has been studied in depth in relation to cardiac development and function. The …

Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

Patients having experienced the ischemia-reperfusion process are particularly vulnerable to
subsequent heart attacks because this process can induce myocardial fibrosis, hallmarked …

Earlier studies revealed the presence of cysteine persulfide (CysSSH) and related
polysulfide species in various mammalian tissues. CysSSH has both antioxidant and oxidant …

Extracorporeal circulation (ECC) systems, including cardiopulmonary bypass, and
extracorporeal membrane oxygenation have been an irreplaceable part of the …

Background The integration of different layers of omics information is an opportunity to tackle
the complexity of cardiovascular diseases (CVD) and to identify new predictive biomarkers …

The effects of hydrogen-rich water on oxidative stress via the Nrf2/ARE signaling pathway
were studied in rats with myocardial ischemia-reperfusion injury (MIRI). Sixty rats were …

Spinal cord injury leads to loss of sensory motor functions below the damaged area, and can
significantly affects physical and mental health. An effective spinal cord injury treatment is …

Myocardial ischemia/reperfusion (I/R) injury is a major cause of mortality and morbidity
worldwide. Among factors contributing to I/R injury, proteolytic enzymes could also cause …

Vascular endothelial cell (EC)-derived factors play an important role in endothelial–
cardiomyocyte crosstalk and could save cardiomyocytes (CMs) from injury. The …