[HTML][HTML] Pros and cons of ultra-high-field MRI/MRS for human application
Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …
for clinical diagnostic applications and in basic research areas such as cognitive …
The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …
Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T
D Paech, J Windschuh, J Oberhollenzer… - Neuro …, 2018 - academic.oup.com
Background Early identification of prognostic superior characteristics in glioma patients such
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …
Review and consensus recommendations on clinical APT‐weighted imaging approaches at 3T: application to brain tumors
Amide proton transfer‐weighted (APTw) MR imaging shows promise as a biomarker of brain
tumor status. Currently used APTw MRI pulse sequences and protocols vary substantially …
tumor status. Currently used APTw MRI pulse sequences and protocols vary substantially …
Downfield‐NOE‐suppressed amide‐CEST‐MRI at 7 Tesla provides a unique contrast in human glioblastoma
Purpose The chemical exchange saturation transfer (CEST) effect observed in brain tissue
in vivo at the frequency offset 3.5 ppm downfield of water was assigned to amide protons of …
in vivo at the frequency offset 3.5 ppm downfield of water was assigned to amide protons of …
Snapshot‐CEST: optimizing spiral‐centric‐reordered gradient echo acquisition for fast and robust 3D CEST MRI at 9.4 T
Gradient echo (GRE)‐based acquisition provides a robust readout method for chemical
exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST …
exchange saturation transfer (CEST) at ultrahigh field (UHF). To develop a snapshot‐CEST …
Relaxation-compensated amide proton transfer (APT) MRI signal intensity is associated with survival and progression in high-grade glioma patients
D Paech, C Dreher, S Regnery, JE Meissner… - European …, 2019 - Springer
Objectives The purpose of this study was to investigate the association of relaxation-
compensated chemical exchange saturation transfer (CEST) MRI with overall survival (OS) …
compensated chemical exchange saturation transfer (CEST) MRI with overall survival (OS) …
Early response assessment of glioma patients to definitive chemoradiotherapy using chemical exchange saturation transfer imaging at 7 T
JE Meissner, A Korzowski, S Regnery… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Patients with newly diagnosed inoperable glioma receive chemoradiotherapy
(CRT). Standard Response Assessment in Neuro‐Oncology (RANO) takes a minimum of 4 …
(CRT). Standard Response Assessment in Neuro‐Oncology (RANO) takes a minimum of 4 …
3D gradient echo snapshot CEST MRI with low power saturation for human studies at 3T
A Deshmane, M Zaiss, T Lindig, K Herz… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose For clinical implementation, a chemical exchange saturation transfer (CEST)
imaging sequence must be fast, with high signal‐to‐noise ratio (SNR), 3D coverage, and …
imaging sequence must be fast, with high signal‐to‐noise ratio (SNR), 3D coverage, and …
Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI
The goal of this study was to develop a molecular biomarker for the detection of protein
aggregation involved in Alzheimer's disease (AD) by exploiting the features of the water …
aggregation involved in Alzheimer's disease (AD) by exploiting the features of the water …