Low-temperature cracking is one of the most prevalent distress in asphalt pavement, closely
related to the bitumen low-temperature properties. However, the molecular mechanism of …

Glycosylation is a promising strategy for modulating the physicochemical properties of
peptides. However, the influence of glycosylation on the biological activities of peptides …

The level of accuracy that can be achieved by a force field is influenced by choices made in
the interaction-function representation and in the relevant simulation parameters. These …

An unprecedented research effort has been undertaken in response to the ongoing COVID-
19 pandemic. This has included the determination of hundreds of crystallographic structures …

Protein–protein interaction (PPI) is one of the key regulatory features driving biomolecular
processes and hence is targeted for designing therapeutics against diseases. Small …

HYL derived from the venom of the solitary bee Hylaeus signatus (Hymenoptera: Colletidae)
is an α-helical antimicrobial peptide with 16 residues. To explore whether HYL can be …

The characterization of protein–protein interactions (PPIs) is an important step toward the
development of therapeutic strategies. In this regard, the use of quantum calculations …

Interfacial tension is an important parameter in enhanced oil recovery (EOR). The interaction
between water and oil phase is a determinant factor of the interfacial tension. The interfacial …

In the field of biomedicine, a critical pursuit is to understand how the immune system
combats viral infections and cancer. The cellular immune response relies on Human …

RESUMO A via PI3K/AKT/mTOR está diretamente envolvida na regulação das principais
vias metabólicas celulares em mamíferos. Alterações nesta via estão relacionadas à …