Triptolide, a compound isolated from a Chinese medicinal herb, possesses potent antitumor,
immunosuppressive, and anti-inflammatory properties, but is clinically limited due to its poor …

Abstract Background Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …

Conventional therapies for cancer treatment have posed many challenges, including toxicity,
multidrug resistance and economic expenses. In contrast, complementary alternative …

Cancer stem cells (CSCs) constitute a subpopulation of tumor cells that possess self-
renewal and tumor initiation capacity, and the ability to give rise to the heterogeneous …

Tocotrienols, found in several natural sources such as rice bran, annatto seeds, and palm oil
have been reported to exert various beneficial health promoting properties especially …

The spread of metastatic cancer cell is the main cause of death worldwide. Cellular and
molecular basis of the action of phytochemicals in the modulation of metastatic cancer …

Cancer stem cells (CSCs) have the ability to self-renew and induce drug resistance and
recurrence in colorectal cancer (CRC). As current chemotherapy doesn't eliminate CSCs …

Doublecortin-like kinase 1 (DCLK1), a protein molecule, has been identified as a tumor stem
cell marker in the cancer cells of gastrointestinal, pancreas, and human colon. DCLK1 …

Naturally occurring phytochemicals or plant derivatives are now being explored extensively
for their health's benefits and medicinal uses. The therapeutic effect of phytochemicals has …

Although the application of multiple chemotherapy brought revolutionary changes to
improve overall survival of osteosarcoma patients, the existence of multidrug resistance …