Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

Dithiocarbamates are considered as an important motif owing to its extensive biological
applications in medicinal chemistry. The synthesis of this framework can easily be achieved …

Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …

New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on
AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines …

Chalcones are α, β unsaturated aromatic ketones having enone moiety and exhibit a wide
array of pharmaceutical and biological activities. Chalcones possess a wide range of …

Aim: There is a continuous and urgent need for new anticancer agents with novel structures
and target selectivity. Methods & results: The anticancer activity of the prepared compounds …

Aim: This paper aims to describe the structure activity relationship of heterocyclic derivatives
with multi-targeted anticancer activity. Objectives: With the following goals in mind, this …

Recent studies have shown that phosphoinositide 3-kinase (PI3K) plays a vital role in cell
division, and it has become a therapeutic target for many cancers. In this paper, some new 1 …

Dithiocarbamates are considered as the simplest occurring organosulfur compounds
exhibiting diverse chemical and medicinal versatility. Dithiocarbamates have been used as …