Chiral non-racemic N-cyanomethyloxazolidines: the pivotal system of the CN (R, S) method

HP Husson, J Royer - Chemical Society Reviews, 1999 - pubs.rsc.org
The α-cyanomethyloxazolidine ring system has been integrated into piperidine and
pyrrolidine structures providing chiral non-racemic building blocks. Reaction conditions …

One-pot cascade synthesis of mono-and disubstituted piperidines and pyrrolidines using carboxylic acid reductase (CAR), ω-transaminase (ω-TA), and imine …

SP France, S Hussain, AM Hill, LJ Hepworth… - Acs …, 2016 - ACS Publications
Access to enantiomerically pure chiral mono-and disubstituted piperidines and pyrrolidines
has been achieved using a biocatalytic cascade involving carboxylic acid reductase (CAR) …

Chiral Oxazolopiperidone Lactams: Versatile Intermediates for the Enantioselective Synthesis of Piperidine‐Containing Natural Products

C Escolano, M Amat, J Bosch - Chemistry–A European Journal, 2006 - Wiley Online Library
Phenylglycinol‐derived oxazolopiperidone lactams are exceptionally versatile building
blocks for the enantioselective construction of structurally diverse piperidine‐containing …

Highly diastereoselective arylations of substituted piperidines

S Seel, T Thaler, K Takatsu, C Zhang… - Journal of the …, 2011 - ACS Publications
A highly diastereoselective methodology for the preparation of various substituted
piperidines via Negishi cross-couplings with (hetero) aryl iodides was developed …

Stereoselective synthesis of piperidines

S Laschat, T Dickner - Synthesis, 2000 - thieme-connect.com
Stereoselective Synthesis of Piperidines Page 1 REVIEW 1781 Synthesis 2000, No. 13,
1781–1813 ISSN 0039-7881 © Thieme Stuttgart · New York Stereoselective Synthesis of …

Saturated nitrogen heterocycles

A Mitchinson, A Nadin - Journal of the Chemical Society, Perkin …, 1999 - pubs.rsc.org
Saturated nitrogen heterocycles Page 1 REVIEW J. Chem. Soc., Perkin Trans. 1, 1999, 2553–2581
2553 This journal is © The Royal Society of Chemistry 1999 Saturated nitrogen …

Nonracemic Betti Base as a New Chiral Auxiliary:  Application to Total Syntheses of Enantiopure (2S,6R)-Dihydropinidine and (2S,6R)-Isosolenopsins

X Wang, Y Dong, J Sun, X Xu, R Li… - The Journal of Organic …, 2005 - ACS Publications
Total syntheses of enantiopure alkaloidal natural products (2 S, 6 R)-dihydropinidine (as
hydrochloride) and (2 S, 6 R)-isosolenopsins (as hydrochlorides) were achieved in four …

Dynamic kinetic resolution and desymmetrization processes: A straightforward methodology for the enantioselective synthesis of piperidines

M Amat, O Bassas, N Llor, M Cantó… - … A European Journal, 2006 - Wiley Online Library
A straightforward procedure for the synthesis of enantiopure polysubstituted piperidines is
reported. It involves the direct generation of chiral non‐racemic oxazolo [3, 2‐a] piperidone …

Asymmetric Synthesis of Ring Functionalized trans-2,6-Disubstituted Piperidines from N-Sulfinyl δ-Amino β-Keto Phosphonates. Total Synthesis of (−)-Myrtine

FA Davis, H Xu, J Zhang - The Journal of organic chemistry, 2007 - ACS Publications
Asymmetric Synthesis of Ring Functionalized trans-2,6-Disubstituted Piperidines from N-Sulfinyl
δ-Amino β-Keto Phosphonates. Total Synthesis of (−)-Myrtine | The Journal of Organic Chemistry …

Tandem Overman Rearrangement and Intramolecular Amidomercuration Reactions. Stereocontrolled Synthesis of cis- and trans-2,6-Dialkylpiperidines

OV Singh, H Han - Organic Letters, 2004 - ACS Publications
Hg (II)-mediated tandem Overman rearrangement and intramolecular amidomercuration
reactions were proven to provide a convenient tool for the stereoselective synthesis of cis …