The plasma membrane as a mechanochemical transducer
AL Le Roux, X Quiroga, N Walani… - … of the Royal …, 2019 - royalsocietypublishing.org
Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …
and respond to. By forming a physical boundary between cells and their environment that is …
Spoiled for choice: diverse endocytic pathways function at the cell surface
JJ Thottacherry, M Sathe… - Annual review of cell …, 2019 - annualreviews.org
Endocytosis has long been identified as a key cellular process involved in bringing in
nutrients, in clearing cellular debris in tissue, in the regulation of signaling, and in …
nutrients, in clearing cellular debris in tissue, in the regulation of signaling, and in …
The 2018 biomembrane curvature and remodeling roadmap
P Bassereau, R Jin, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …
recognized for many years and has fascinated scientists from a wide range of different …
Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosis
Force generation by actin assembly shapes cellular membranes. An experimentally
constrained multiscale model shows that a minimal branched actin network is sufficient to …
constrained multiscale model shows that a minimal branched actin network is sufficient to …
Systematic nanoscale analysis of endocytosis links efficient vesicle formation to patterned actin nucleation
Clathrin-mediated endocytosis is an essential cellular function in all eukaryotes that is driven
by a self-assembled macromolecular machine of over 50 different proteins in tens to …
by a self-assembled macromolecular machine of over 50 different proteins in tens to …
A flat BAR protein promotes actin polymerization at the base of clathrin-coated pits
Multiple proteins act co-operatively in mammalian clathrin-mediated endocytosis (CME) to
generate endocytic vesicles from the plasma membrane. The principles controlling the …
generate endocytic vesicles from the plasma membrane. The principles controlling the …
Upregulation of APP endocytosis by neuronal aging drives amyloid-dependent synapse loss
Neuronal aging increases the risk of late-onset Alzheimer's disease. During normal aging,
synapses decline, and β-amyloid (Aβ) accumulates intraneuronally. However, little is known …
synapses decline, and β-amyloid (Aβ) accumulates intraneuronally. However, little is known …
Actin dynamics drive cell-like membrane deformation
Cell membrane deformations are crucial for proper cell function. Specialized protein
assemblies initiate inward or outward membrane deformations that the cell uses respectively …
assemblies initiate inward or outward membrane deformations that the cell uses respectively …
Molecular mechanisms of force production in clathrin‐mediated endocytosis
During clathrin‐mediated endocytosis (CME), a flat patch of membrane is invaginated and
pinched off to release a vesicle into the cytoplasm. In yeast CME, over 60 proteins …
pinched off to release a vesicle into the cytoplasm. In yeast CME, over 60 proteins …
Membrane bending by actin polymerization
AE Carlsson - Current opinion in cell biology, 2018 - Elsevier
Actin polymerization provides driving force to aid several types of processes that involve
pulling the plasma membrane into the cell, including phagocytosis, cellular entry of large …
pulling the plasma membrane into the cell, including phagocytosis, cellular entry of large …