Biosensors are a very active research field. They have the potential to lead to low-cost,
rapid, sensitive, reproducible, and miniaturized bioanalytical devices, which exploit the high …

Proteases play a pivotal role in regulating important physiological processes from food
digestion to blood clotting. They are also important biomarkers for many diseases such as …

The demand for point-of-need (PON) diagnostics for clinical and other applications is
continuing to grow. Much of this demand is currently serviced by biosensors, which combine …

Optically enhanced biosensing strategies are prerequisites for developing miniature and
highly sensitive multiplexed analytical platforms. Such smart biosensing systems are highly …

We present a paper-based system that integrates bioluminescence resonance energy
transfer (BRET) and isothermal amplification for the analysis of tumor-associated circulating …

Proteases are a group of enzymes with a catalytic function to hydrolyze peptide bonds of
proteins. Proteases regulate the activity, signaling mechanism, fate, and localization of many …

We have previously shown that a genetically encoded bioluminescent resonance energy
transfer (BRET) biosensor, comprising maltose binding protein (MBP) flanked by a green …

Bioluminescence resonance energy transfer (BRET) is a sensitive optical detection method
that can monitor changes in the relative orientation and the physical proximity of molecules …

Bacterial proteases are sporadic contributors to milk spoilage, reducing the quality of ultra-
heat treated (UHT) milk and other dairy products. Current methods for measuring bacterial …

The number of receptors expressed by cells plays an important role in controlling cell
signaling events, thus determining its behaviour, state and fate. Current methods of …