Therapeutic potential of marine peptides in malignant melanoma

S Ahmed, W Alam, KF Alsharif, M Aschner… - Environmental …, 2023 - Elsevier
Malignant melanoma is the most dangerous type of skin cancer. It is becoming more
common globally and is increasingly resistant to treatment options. Despite extensive …

Approach of multiple endocrine neoplasia type 1 (MEN1) syndrome–related skin tumors

LC Băicoianu-Nițescu, AM Gheorghe, M Carsote… - Diagnostics, 2022 - mdpi.com
Non-endocrine findings in patients with MEN1 (multiple endocrine neoplasia) syndrome
also include skin lesions, especially tumor-type lesions. This is a narrative review of the …

Antiproliferative and Proapoptotic Effects of Erucin, A Diet-Derived H2S Donor, on Human Melanoma Cells

DC Maresca, L Conte, B Romano, A Ianaro, G Ercolano - Antioxidants, 2022 - mdpi.com
Melanoma is the most dangerous form of skin cancer and is characterized by chemotherapy
resistance and recurrence despite the new promising therapeutic approaches. In the last …

Tetrahedral framework nucleic acid loaded with glabridin: A transdermal delivery system applicated to anti‐hyperpigmentation

J He, W Chen, X Chen, Y Xie, Y Zhao, T Tian… - Cell …, 2023 - Wiley Online Library
Topical application of tyrosinase inhibitors, such as hydroquinone and arbutin, is the most
common clinical treatment for hyperpigmentation. Glabridin (Gla) is a natural isoflavone that …

A new strategy for the treatment of Parkinson's disease: Discovery and bio-evaluation of the first central-targeting tyrosinase inhibitor

S Qi, L Guo, J Liang, K Wang, Q Liao, S He, W Lyu… - Bioorganic …, 2024 - Elsevier
The high level of tyrosinase leads to the generation of neuromelanin, further causing the
abnormality of redox-related protein level and mediating the occurrence and development of …

[HTML][HTML] Vaginal mucosal melanoma cell activation in response to photon or carbon ion irradiation

A Charalampopoulou, A Barcellini, M Bistika… - International Journal of …, 2024 - Elsevier
Purpose Primary gynecological melanomas are uncommon with lower survival rates
compared to cutaneous melanomas. Although melanocytes have been identified in a variety …

[HTML][HTML] Polyphenol Profile and Antioxidant, Antityrosinase, and Anti-Melanogenesis Activities of Ethanol Extract of Bee Pollen

Q He, J Wang, J Li, W Yang - Pharmaceuticals, 2024 - mdpi.com
Background/Objective: Bee pollen, a rich nutritional food, was employed to develop a raw
material for skin whitening. Methods: The polyphenol profile and antioxidant, antityrosinase …

Tumor-Intrinsic Galectin-3 Suppresses Melanoma Metastasis

NBB Mohammed, LS Lau, J Souchak, S Qiu… - Journal of Investigative …, 2024 - Elsevier
Melanoma poses a poor prognosis with high mortality rates upon metastasis. Exploring the
molecular mechanisms governing melanoma progression paves the way for developing …

Size selection of intrahepatic lesions for cryoablation contributes to abscopal effect and long-term survival in patients with liver metastatic melanoma receiving PD-1 …

L Shen, H Tan, J Nie, Y Jiang, G Nuerhashi… - Cancer Immunology …, 2024 - Springer
Objectives In this study, we aimed to examine parameters of cryoablation, tumor
characteristics, and their correlations with distant tumor response and survival of liver …

In vitro/in vivo translation of synergistic combination of MDM2 and MEK inhibitors in melanoma using PBPK/PD modelling: part III

J Witkowski, S Polak, D Pawelec… - International Journal of …, 2023 - mdpi.com
The development of in vitro/in vivo translational methods and a clinical trial framework for
synergistically acting drug combinations are needed to identify optimal therapeutic …