Silica nanoparticles—a versatile tool for the treatment of bacterial infections

V Selvarajan, S Obuobi, PLR Ee - Frontiers in Chemistry, 2020 - frontiersin.org
The rapid emergence of drug resistance continues to outpace the development of new
antibiotics in the treatment of infectious diseases. Conventional therapy is currently limited …

Mesoporous silica particles as drug delivery systems—the state of the art in loading methods and the recent progress in analytical techniques for monitoring these …

K Trzeciak, A Chotera-Ouda, II Bak-Sypien… - Pharmaceutics, 2021 - mdpi.com
Conventional administration of drugs is limited by poor water solubility, low permeability,
and mediocre targeting. Safe and effective delivery of drugs and therapeutic agents remains …

Nanomachines and other caps on mesoporous silica nanoparticles for drug delivery

W Chen, CA Glackin, MA Horwitz… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Mesoporous silica nanoparticles (MSNs) are delivery vehicles that can carry
cargo molecules and release them on command. The particles used in the applications …

Shortwave infrared imaging with J-aggregates stabilized in hollow mesoporous silica nanoparticles

W Chen, CA Cheng, ED Cosco… - Journal of the …, 2019 - ACS Publications
Tissue is translucent to shortwave infrared (SWIR) light, rendering optical imaging superior
in this region. However, the widespread use of optical SWIR imaging has been limited, in …

Mesoporous silica nanoparticles as delivery carriers: An overview of drug loading techniques

KB Seljak, P Kocbek, M Gašperlin - Journal of Drug Delivery Science and …, 2020 - Elsevier
Mesoporous silica nanoparticles (MSNs) are arising as a promising delivery system for a
more effective and safer therapy of many diseases, such as cancer, osteoporosis and …

An ultrasensitive split-type electrochemical immunosensor based on controlled-release strategy for detection of CA19-9

B Li, Y Li, C Li, J Yang, D Liu, H Wang, R Xu… - Biosensors and …, 2023 - Elsevier
In this study, a novel split-type electrochemical immunosensor based on controlled release
strategy was proposed for sensitive analysis and detection of tumor marker carbohydrate …

Silicon-containing nanomedicine and biomaterials: materials chemistry, multi-dimensional design, and biomedical application

L Chen, S Zhang, Y Duan, X Song, M Chang… - Chemical Society …, 2024 - pubs.rsc.org
The invention of silica-based bioactive glass in the late 1960s has sparked significant
interest in exploring a wide range of silicon-containing biomaterials from the macroscale to …

Clofazimine for the treatment of tuberculosis

JAM Stadler, G Maartens, G Meintjes… - Frontiers in …, 2023 - frontiersin.org
Shorter (6–9 months), fully oral regimens containing new and repurposed drugs are now the
first-choice option for the treatment of drug-resistant tuberculosis (DR-TB). Clofazimine, long …

[HTML][HTML] Supramolecular nanomachines as stimuli-responsive gatekeepers on mesoporous silica nanoparticles for antibiotic and cancer drug delivery

CA Cheng, T Deng, FC Lin, Y Cai, JI Zink - Theranostics, 2019 - ncbi.nlm.nih.gov
Major objectives in nanomedicine and nanotherapy include the ability to trap therapeutic
molecules inside of nano-carriers, carry therapeutics to the site of the disease with no …

Recent technologies for amorphization of poorly water-soluble drugs

D Kim, Y Kim, YY Tin, MTP Soe, B Ko, S Park, J Lee - Pharmaceutics, 2021 - mdpi.com
Amorphization technology has been the subject of continuous attention in the
pharmaceutical industry, as a means to enhance the solubility of poorly water-soluble drugs …