Lung cancer (LC) is the most common cancer-related death globally, and many efforts have
been made to improve the patient care of LC patients, as well as the development of efficient …

Exosomes are a novel class of intercellular signal modulators that contain a wide range of
molecules and deliver information between cells and tissues. MicroRNAs (miRNAs), a type …

Activation of the KRAS oncogene is a source of replication stress, but how this stress is
generated and how it is tolerated by cancer cells remain poorly understood. Here we show …

Lung cancer is the leading cause of cancer-related deaths worldwide. KRAS is the main
oncogenic driver in lung cancer that can be activated by gene mutation or amplification, but …

There is an urgent unmet need for robust and reliable biomarkers for early diagnosis,
prognosis, and prediction of response to specific treatments of many aggressive and deadly …

AIM To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the
microenvironment of colonic neoplasms and the expression of inflammatory mediators and …

Cancer is amongst the deadliest and most disruptive disorders, having a much higher death
rate than other diseases worldwide. Human cancer rates continue to rise, thereby posing the …

Lung cancer is one of the most common cancers worldwide and the leading cause of death.
Early screening of lung cancer is exceptionally essential for later treatment. Abnormal lung …

Ras p21 protein activator 1 (RASA1) is a regulator of Ras GDP and GTP and is involved in
numerous physiological processes such as angiogenesis, cell proliferation, and apoptosis …

K-Ras frequently acquires gain-of-function mutations (K-Ras G12D being the most common)
that trigger significant transcriptomic and proteomic changes to drive tumorigenesis …