[HTML][HTML] Biomarkers for the Detection and Risk Stratification of Aggressive Prostate Cancer
S Eickelschulte, AL Riediger, AK Angeles, F Janke… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …
From odor to oncology: non-canonical odorant receptors in cancer
Odorant receptors, traditionally associated with olfaction as chemoreceptors, have been
increasingly recognized for their presence and diverse functions in various non-nasal …
increasingly recognized for their presence and diverse functions in various non-nasal …
[HTML][HTML] VIRMA-dependent N6-methyladenosine modifications regulate the expression of long non-coding RNAs CCAT1 and CCAT2 in prostate cancer
D Barros-Silva, J Lobo, C Guimarães-Teixeira… - Cancers, 2020 - mdpi.com
RNA methylation at position N6 in adenosine (m6A) and its associated methyltransferase
complex (MTC) are involved in tumorigenesis. We aimed to explore m6A biological function …
complex (MTC) are involved in tumorigenesis. We aimed to explore m6A biological function …
Cytoplasmic cyclin E mediates resistance to aromatase inhibitors in breast cancer
I Doostan, C Karakas, M Kohansal, KH Low… - Clinical Cancer …, 2017 - AACR
Purpose: Preoperative aromatase inhibitor (AI) therapy has demonstrated efficacy in
hormone receptor (HR)-positive postmenopausal breast cancer. However, many patients …
hormone receptor (HR)-positive postmenopausal breast cancer. However, many patients …
[HTML][HTML] Utility of circulating cell-free RNA analysis for the characterization of global transcriptome profiles of multiple myeloma patients
M Chen, S Mithraprabhu, M Ramachandran, K Choi… - Cancers, 2019 - mdpi.com
In this study, we evaluated the utility of extracellular RNA (exRNA) derived from the plasma
of multiple myeloma (MM) patients for whole transcriptome characterization. exRNA from 10 …
of multiple myeloma (MM) patients for whole transcriptome characterization. exRNA from 10 …
[HTML][HTML] Characterization of soft amyloid cores in human prion-like proteins
Prion-like behaviour is attracting much attention due to the growing evidences that amyloid-
like self-assembly may reach beyond neurodegeneration and be a conserved functional …
like self-assembly may reach beyond neurodegeneration and be a conserved functional …
[HTML][HTML] Prognostic values of gene copy number alterations in prostate cancer
Whilst risk prediction for individual prostate cancer (PCa) cases is of a high priority, the
current risk stratification indices for PCa management have severe limitations. This study …
current risk stratification indices for PCa management have severe limitations. This study …
[HTML][HTML] Induction of acquired resistance towards EGFR inhibitor gefitinib in a patient-derived xenograft model of non-small cell lung cancer and subsequent molecular …
J Schueler, C Tschuch, K Klingner, D Bug, AL Peille… - Cells, 2019 - mdpi.com
In up to 30% of non-small cell lung cancer (NSCLC) patients, the oncogenic driver of tumor
growth is a constitutively activated epidermal growth factor receptor (EGFR). Although these …
growth is a constitutively activated epidermal growth factor receptor (EGFR). Although these …
[HTML][HTML] Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer
Abstract In the United States alone one in five newly diagnosed cancers in men are prostate
carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal …
carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal …
[HTML][HTML] Gain of TPPP as a predictor of progression in patients with bladder cancer
YH Chang, PH Lin, CC Chen… - Experimental and …, 2021 - spandidos-publications.com
The present study investigated the role of tubulin polymerization promoting protein (TPPP) in
the regulation of bladder cancer (BC) cell proliferation and migration, in addition to the …
the regulation of bladder cancer (BC) cell proliferation and migration, in addition to the …