[HTML][HTML] Biomarkers for the Detection and Risk Stratification of Aggressive Prostate Cancer

S Eickelschulte, AL Riediger, AK Angeles, F Janke… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …

From odor to oncology: non-canonical odorant receptors in cancer

SJ Park, PL Greer, N Lee - Oncogene, 2024 - nature.com
Odorant receptors, traditionally associated with olfaction as chemoreceptors, have been
increasingly recognized for their presence and diverse functions in various non-nasal …

[HTML][HTML] VIRMA-dependent N6-methyladenosine modifications regulate the expression of long non-coding RNAs CCAT1 and CCAT2 in prostate cancer

D Barros-Silva, J Lobo, C Guimarães-Teixeira… - Cancers, 2020 - mdpi.com
RNA methylation at position N6 in adenosine (m6A) and its associated methyltransferase
complex (MTC) are involved in tumorigenesis. We aimed to explore m6A biological function …

Cytoplasmic cyclin E mediates resistance to aromatase inhibitors in breast cancer

I Doostan, C Karakas, M Kohansal, KH Low… - Clinical Cancer …, 2017 - AACR
Purpose: Preoperative aromatase inhibitor (AI) therapy has demonstrated efficacy in
hormone receptor (HR)-positive postmenopausal breast cancer. However, many patients …

[HTML][HTML] Utility of circulating cell-free RNA analysis for the characterization of global transcriptome profiles of multiple myeloma patients

M Chen, S Mithraprabhu, M Ramachandran, K Choi… - Cancers, 2019 - mdpi.com
In this study, we evaluated the utility of extracellular RNA (exRNA) derived from the plasma
of multiple myeloma (MM) patients for whole transcriptome characterization. exRNA from 10 …

[HTML][HTML] Characterization of soft amyloid cores in human prion-like proteins

C Batlle, NS De Groot, V Iglesias, S Navarro… - Scientific reports, 2017 - nature.com
Prion-like behaviour is attracting much attention due to the growing evidences that amyloid-
like self-assembly may reach beyond neurodegeneration and be a conserved functional …

[HTML][HTML] Prognostic values of gene copy number alterations in prostate cancer

A Alfahed, HO Ebili, NE Almoammar, G Alasiri… - Genes, 2023 - mdpi.com
Whilst risk prediction for individual prostate cancer (PCa) cases is of a high priority, the
current risk stratification indices for PCa management have severe limitations. This study …

[HTML][HTML] Induction of acquired resistance towards EGFR inhibitor gefitinib in a patient-derived xenograft model of non-small cell lung cancer and subsequent molecular …

J Schueler, C Tschuch, K Klingner, D Bug, AL Peille… - Cells, 2019 - mdpi.com
In up to 30% of non-small cell lung cancer (NSCLC) patients, the oncogenic driver of tumor
growth is a constitutively activated epidermal growth factor receptor (EGFR). Although these …

[HTML][HTML] Systems pharmacology using mass spectrometry identifies critical response nodes in prostate cancer

HA Ebhardt, A Root, Y Liu, NP Gauthier… - NPJ systems biology …, 2018 - nature.com
Abstract In the United States alone one in five newly diagnosed cancers in men are prostate
carcinomas (PCa). Androgen receptor (AR) status and the PI3K-AKT-mTOR signal …

[HTML][HTML] Gain of TPPP as a predictor of progression in patients with bladder cancer

YH Chang, PH Lin, CC Chen… - Experimental and …, 2021 - spandidos-publications.com
The present study investigated the role of tubulin polymerization promoting protein (TPPP) in
the regulation of bladder cancer (BC) cell proliferation and migration, in addition to the …