Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions

AR Brunoni, MA Nitsche, N Bolognini, M Bikson… - Brain stimulation, 2012 - Elsevier
BACKGROUND: Transcranial direct current stimulation (tDCS) is a neuromodulatory
technique that delivers low-intensity, direct current to cortical areas facilitating or inhibiting …

Animal models of transcranial direct current stimulation: methods and mechanisms

MP Jackson, A Rahman, B Lafon, G Kronberg… - Clinical …, 2016 - Elsevier
The objective of this review is to summarize the contribution of animal research using direct
current stimulation (DCS) to our understanding of the physiological effects of transcranial …

Measurements and models of electric fields in the in vivo human brain during transcranial electric stimulation

Y Huang, AA Liu, B Lafon, D Friedman, M Dayan… - elife, 2017 - elifesciences.org
Transcranial electric stimulation aims to stimulate the brain by applying weak electrical
currents at the scalp. However, the magnitude and spatial distribution of electric fields in the …

Realistic volumetric-approach to simulate transcranial electric stimulation—ROAST—a fully automated open-source pipeline

Y Huang, A Datta, M Bikson… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Research in the area of transcranial electrical stimulation (TES) often relies on
computational models of current flow in the brain. Models are built based on magnetic …

Electric field depth–focality tradeoff in transcranial magnetic stimulation: simulation comparison of 50 coil designs

ZD Deng, SH Lisanby, AV Peterchev - Brain stimulation, 2013 - Elsevier
BACKGROUND: Various transcranial magnetic stimulation (TMS) coil designs are available
or have been proposed. However, key coil characteristics such as electric field focality and …

Comparing cortical plasticity induced by conventional and high-definition 4× 1 ring tDCS: a neurophysiological study

HI Kuo, M Bikson, A Datta, P Minhas, W Paulus… - Brain stimulation, 2013 - Elsevier
Background Transcranial direct current stimulation (tDCS) induces long-lasting NMDA
receptor-dependent cortical plasticity via persistent subthreshold polarization of neuronal …

Gyri-precise head model of transcranial direct current stimulation: improved spatial focality using a ring electrode versus conventional rectangular pad

A Datta, V Bansal, J Diaz, J Patel, D Reato, M Bikson - Brain stimulation, 2009 - Elsevier
The spatial resolution of conventional transcranial direct current stimulation (tDCS) is
considered to be relatively diffuse owing to skull dispersion. However, we show that electric …

Determinants of the electric field during transcranial direct current stimulation

A Opitz, W Paulus, S Will, A Antunes, A Thielscher - Neuroimage, 2015 - Elsevier
Transcranial direct current stimulation (tDCS) causes a complex spatial distribution of the
electric current flow in the head which hampers the accurate localization of the stimulated …

Inter-individual variation during transcranial direct current stimulation and normalization of dose using MRI-derived computational models

A Datta, D Truong, P Minhas, LC Parra… - Frontiers in …, 2012 - frontiersin.org
Background: Transcranial Direct Current Stimulation (tDCS) is a non-invasive, versatile, and
safe neuromodulation technology under investigation for the treatment of neuropsychiatric …

Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: a basis for high-definition tDCS

D Edwards, M Cortes, A Datta, P Minhas… - Neuroimage, 2013 - Elsevier
Transcranial Direct Current Stimulation (tDCS) is a non-invasive, low-cost, well-tolerated
technique producing lasting modulation of cortical excitability. Behavioral and therapeutic …