Eukaryotic nucleosomes organize chromatin by wrapping 147 bp of DNA around a histone
core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA …

Nucleosomes wrap DNA and impede access for the machinery of transcription. The core
histones that constitute nucleosomes are subject to a diversity of posttranslational …

In nature, plants are often subjected to periods of recurrent environmental stress that can
strongly affect their development and productivity. To cope with these conditions, plants can …

Nucleosome dynamics and properties are central to all forms of genomic activities. Among
the core histones, H3 variants play a pivotal role in modulating nucleosome structure and …

Histone H3. 3 is an H3 variant which differs from the canonical H3. 1/2 at four residues,
including a serine residue at position 31 which is evolutionarily conserved. The H3. 3 S31 …

Vertebrates exhibit specific requirements for replicative H3 and non-replicative H3. 3
variants during development. To disentangle whether this involves distinct modes of …

Abstract Bryant-Li-Bhoj syndrome (BLBS), which became OMIM-classified in 2022 (OMIM:
619720, 619721), is caused by germline variants in the two genes that encode histone H3. 3 …

Epigenetic information contributes to proper gene expression and development, and can be
transmitted not only through mitotic divisions but also from parents to progeny. We …

Histone proteins organize nuclear DNA in eukaryotic cells and play crucial roles in
regulating chromatin structure and function. Histone variants are produced by distinct …

The eukaryotic nucleus controls most cellular processes. It is isolated from the cytoplasm by
the nuclear envelope, which plays a prominent role in the structural organization of the cell …