[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Biomimetic peptide self-assembly for functional materials

A Levin, TA Hakala, L Schnaider… - Nature Reviews …, 2020 - nature.com
Natural biomolecular systems have evolved to form a rich variety of supramolecular
materials and machinery fundamental to cellular function. The assembly of these structures …

[HTML][HTML] Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application

W Chiangjong… - … Journal of Oncology, 2020 - spandidos-publications.com
Cancer is currently ineffectively treated using therapeutic drugs, and is also able to resist
drug action, resulting in increased side effects following drug treatment. A novel therapeutic …

[HTML][HTML] Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo

P Kumar, JN Kizhakkedathu, SK Straus - Biomolecules, 2018 - mdpi.com
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …

[HTML][HTML] Antimicrobial peptides as anticancer agents: functional properties and biological activities

AL Tornesello, A Borrelli, L Buonaguro, FM Buonaguro… - Molecules, 2020 - mdpi.com
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …

Mini review on antimicrobial peptides, sources, mechanism and recent applications

JK Boparai, PK Sharma - Protein and peptide letters, 2020 - ingentaconnect.com
Antimicrobial peptides in recent years have gained increased interest among scientists,
health professionals and the pharmaceutical companies owing to their therapeutic potential …

Peptide design principles for antimicrobial applications

MDT Torres, S Sothiselvam, TK Lu… - Journal of molecular …, 2019 - Elsevier
The increased incidence of bacterial resistance to available antibiotics represents a major
global health problem and highlights the need for novel anti-infective therapies …

Considerations and caveats in combating ESKAPE pathogens against nosocomial infections

YX Ma, CY Wang, YY Li, J Li, QQ Wan… - Advanced …, 2020 - Wiley Online Library
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

[HTML][HTML] Reassessing the host defense peptide landscape

EF Haney, SK Straus, REW Hancock - Frontiers in chemistry, 2019 - frontiersin.org
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Antimicrobial peptide-based materials: Opportunities and challenges

A Rai, R Ferrão, P Palma, T Patricio… - Journal of Materials …, 2022 - pubs.rsc.org
The multifunctional properties of antimicrobial peptides (AMPs) make them attractive
candidates for the treatment of various diseases. AMPs are considered as alternatives to …