Almost all bacteria synthesize two types of toxins—one for its survival by regulating different
cellular processes and another as a strategy to interact with host cells for pathogenesis …

Toxin-antitoxin (TA) systems are known to play various roles in physiological processes,
such as gene regulation, growth arrest and survival, in bacteria exposed to environmental …

Toxin-antitoxin (TA) systems play important roles in bacterial physiology, such as multidrug
tolerance, biofilm formation, and arrest of cellular growth under stress conditions. To develop …

Protein–Protein interactions (PPIs) are involved in a myriad of cellular processes in all living
organisms and the modulation of PPIs is already under investigation for the development of …

The identification of novel targets for antimicrobial agents is crucial for combating infectious
diseases caused by evolving bacterial pathogens. Components of bacterial toxin–antitoxin …

The search for new, non-standard targets is currently a high priority in the design of new
antibacterial compounds. Bacterial toxin–antitoxin systems (TAs) are genetic modules that …

Toxin-antitoxin (TA) systems are essential for bacterial persistence under stressful
conditions. In particular, Mycobacterium tuberculosis express VapBC TA genes that encode …

Streptococcus pneumonia has attracted increasing attention due to its resistance to existing
antibiotics. TA systems are essential for bacterial persistence under stressful conditions such …

The most common source of foodborne Salmonella infection in humans is poultry eggs and
meat, such that prevention of human infection is mostly achieved by vaccination of farm …

The bacterial toxin-antitoxin MazEF system in the tuberculosis (TB)-causing bacterium
Mycobacterium tuberculosis is activated under unfavorable conditions, including starvation …