MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-
transcriptionally to regulate gene expression by binding to particular mRNA targets and …

In recent years, major advances have been made in cancer immunotherapy. This has led to
significant improvement in prognosis of cancer patients, especially in the hematological …

Cells must adapt to changes in their environment to maintain cell, tissue and organismal
integrity in the face of mechanical, chemical or microbiological stress. Nuclear factor-κB (NF …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer mortality,
accounting for almost 90% of total liver cancer burden. Surgical resection followed by …

Chromosome 22q11. 2 deletion syndrome (22q11. 2del) is a complex, multi-organ disorder
noted for its varying severity and penetrance among those affected. The clinical problems …

Cancer is a disorder of cell growth and proliferation, characterized by different metabolic
pathways within normal cells. The Warburg effect is a major metabolic process in cancer …

Background Accumulation evidence indicates the vital role of long non-coding RNAs
(lncRNAs) in tumorigenesis and the progression of malignant tumors, including pancreatic …

Hepatocellular Carcinoma (HCC) is one of the most predominant malignancies with high
fatality rate. This deadly cancer is rising at an alarming rate because it is quite resistant to …

Deubiquitylating enzymes (DUBs) are proteases that remove the ubiquitin moiety from
ubiquitylated substrates to antagonize the modification mediated by E3 ubiquitin ligases …

Background—Cigarette smoking increases risk for multiple diseases. MicroRNAs regulate
gene expression and may play a role in smoking-induced target organ damage. We sought …